Structure of PDB 7mpi Chain AX Binding Site BS02

Receptor Information

>7mpi Chain AX (length=121) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

KALKVRTSATFRLPKTLKLARAPKYASKAVPHYNRLDSYKVIEQPITSET
AMKKVEDGNILVFQVSMKANKYQIKKAVKELYEVDVLKVNTLVRPNGTKK
AYVRLTADYDALDIANRIGYI

Ligand information

>7mpi Chain A4 (length=158) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

aaacuuucaacaacggaucucuugguucucgcaucgaugaagaacgcagc
gaaaugcgauacguaaugugaauugcagaauuccgugaaucaucgaaucu
uugaacgcacauugcgccccuugguauuccagggggcaugccuguuugag
cgucauuu

.........................................<<<<<<.<<
.....>>>.....(.<<<......>>..............>>>..)...>
>>....<<.....>><<<<<<<<<....>>>>>>>>>.............
........

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7mpi CryoEM structures of pseudouridine-free ribosome suggest impacts of chemical modifications on ribosome conformations.
Resolution	3.05 Å
Binding residue (original residue number in PDB)	K22 L24 R27 T37 L38 R42 S48 K49 H53 Y54 N55 R56 K61 K89 N91 Y93 Q94 K97
Binding residue (residue number reindexed from 1)	K1 L3 R6 T16 L17 R21 S27 K28 H32 Y33 N34 R35 K40 K68 N70 Y72 Q73 K76

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:7mpi, PDBe:7mpi, PDBj:7mpi
PDBsum	7mpi
PubMed	35489333
UniProt	P04456\|RL25_YEAST Large ribosomal subunit protein uL23 (Gene Name=RPL25)

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