Structure of PDB 6p5k Chain AX Binding Site BS02

Receptor Information
>6p5k Chain AX (length=118) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMK
KIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYV
RLAPDYDALDVANKIGII
Ligand information
>6p5k Chain 8 (length=151) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcagguugaucaucgacacuucgaac
gcacuugcggccccggguuccucccggggcuacgccugucugagcgucgc
u
.........................................<<<<<<.<<
.....>>>.....(.<<<......>>........>>>..)...>>>....
<<<..>>><<<<<<<<.......>>>>>>>>...................
.
Receptor-Ligand Complex Structure
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PDB6p5k The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		F46 T51 L52 R55 R56 K63 P66 R67 N69 K70 N105 H107 Q108
Binding residue
(residue number reindexed from 1)		F8 T13 L14 R17 R18 K25 P28 R29 N31 K32 N67 H69 Q70
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6p5k, PDBe:6p5k, PDBj:6p5k
PDBsum6p5k
PubMed31609474
UniProtG1SE76|RL23A_RABIT Large ribosomal subunit protein uL23 (Gene Name=RPL23A)

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