Structure of PDB 4v67 Chain AX Binding Site BS02

Receptor Information
>4v67 Chain AX (length=362) Species: 274 (Thermus thermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NASRNAWKASGGIFDIPQKETRLKELERRLEDPSLWNDPEAARKVSQEAA
RLRRTVDTFRSLESDLQGLLELMEELPAEEREALKPELEEAAKKLDELYH
QTLLNFPHAEKNAILTIQPGAGGTEACDWAEMLLRMYTRFAERQGFQVEV
VDLTPGPEAGIDYAQILVKGENAYGLLSPEAGVHRLVRPSPFDASGRRHT
SFAGVEVIPEVDEEVEVVLKPEELRIDVMRASGPGGQGVNTTDSAVRVVH
LPTGITVTCQTTRSQIKNKELALKILKARLYELERKKREEELKALRGEVR
PIEWGSQIRSYVLDKNYVKDHRTGLMRHDPENVLDGDLMDLIWAGLEWKA
GRRQGTEEVEAE
Ligand information
Receptor-Ligand Complex Structure
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PDB4v67 Crystal structure of a translation termination complex formed with release factor RF2.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		G138 G139 T140 E141 V203 S206 S211 R213 R214 H215 T216
Binding residue
(residue number reindexed from 1)		G122 G123 T124 E125 V187 S190 S195 R197 R198 H199 T200
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003747 translation release factor activity
GO:0016149 translation release factor activity, codon specific
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
GO:0006415 translational termination
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4v67, PDBe:4v67, PDBj:4v67
PDBsum4v67
PubMed19064930
UniProtQ5SM01|RF2_THET8 Peptide chain release factor RF2 (Gene Name=prfB)

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