Structure of PDB 8hl5 Chain AS5P Binding Site BS02

Receptor Information

>8hl5 Chain AS5P (length=204) Species: 330779 (Sulfolobus acidocaldarius DSM 639)

EDWKPRTKVGQLIKEGKINSMKELFERNLPIVEPEIVDVLLPKLRYDIVD
IGIVQKQTDAGELSRYKVLIVMGNMDGYISYGTGKAKQLRVAIQKAIRDA
KMRIIPVRRGCGSWECTCGESHSLPFIVSGKAGSVEVTLLPAPKGTGLVV
GSVLKTFLSLAGLKDVWSRTKGSTYTHENFIKAAYIALYNTYRFVTPVDW
GRMK

Ligand information

• Ligand ID: UNK
• InChI: InChI=1S/C4H9NO2/c1-2-3(5)4(6)7/h3H,2,5H2,1H3,(H,6,7)/t3-/m0/s1
• InChIKey: QWCKQJZIFLGMSD-VKHMYHEASA-N
• SMILES:
  OpenEye OEToolkits 1.5.0: CCC(C(=O)O)N
  OpenEye OEToolkits 1.5.0: CC[C@@H](C(=O)O)N
  CACTVS 3.341: CC[C@H](N)C(O)=O
  CACTVS 3.341: CC[CH](N)C(O)=O
  ACDLabs 10.04: O=C(O)C(N)CC
• Formula: C4 H9 N O2
• Name: UNKNOWN
• ChEMBL: CHEMBL1230782
• ZINC: ZINC000000901351
• PDB chain: 8hl5 Chain AS5P Residue 301

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8hl5 Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome
• Resolution: 5.72 Å
• Binding residue (original residue number in PDB): K37 E41
• Binding residue (residue number reindexed from 1): K22 E26
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0015935 small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8hl5, PDBe:8hl5, PDBj:8hl5
• PDBsum: 8hl5
• PubMed: 37604686
• UniProt: O05641|RS5_SULAC Small ribosomal subunit protein uS5 (Gene Name=rps5)