Structure of PDB 3jbp Chain AR Binding Site BS02

Receptor Information
>3jbp Chain AR (length=252) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KVVKNKAYFKRYQVKYRRRREGKTDYRARKALILQDKNKYNAQKLRFVVR
KTNSQVICQIACAHIEGDKILAEAKSKELIRYGIPVGLKNYAAAYATGLL
CARRFLKSLNLDTQFLGVEKVTRKPIKAFLDVGITRTTTGNRVFAALKGA
CDGGLNIPHGNNRFPGSFNPEQLRKNILGIHVAEYMKTLQEEDNDKYKTH
FNDYLKNNIGADDIEQMYLNAHEKIRQNPKKLNAKLRKKRVKEKLALYVE
LQ
Ligand information
>3jbp Chain AB (length=118) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gacucguucauacuacaguggauacaccagaucccaucagaacucugaag
uuaagcacuguaaggcuuggcuaguacugaggugggagaccgcucgggaa
caccaggugaugagucag
<<<<<<<<....<<<<<<<<.....<<<<<..............>>>..>
>....>>>>>>.>><<<<<<......<<<<<..<<....>>.>>>>>...
..>>>>>>>>>>>>>>..
Receptor-Ligand Complex Structure
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PDB3jbp Dynamical features of the Plasmodium falciparum ribosome during translation.
Resolution6.7 Å
Binding residue
(original residue number in PDB)
K10 F13 K14 Y20 R21 R22 R24 K27 T28 Y30 R33 R50 R54 K55 T56 N57 S58 Q59 Q63 E70 G71 D72 K73 I74 K79 K81 K93 N94 Y95 T153 R154 N159 R160 Y206 H221 F222 N223 D224 Y225 K271 K272 L273 A275 R278 R281 V282 K285
Binding residue
(residue number reindexed from 1)
K6 F9 K10 Y16 R17 R18 R20 K23 T24 Y26 R29 R46 R50 K51 T52 N53 S54 Q55 Q59 E66 G67 D68 K69 I70 K75 K77 K89 N90 Y91 T135 R136 N141 R142 Y185 H200 F201 N202 D203 Y204 K230 K231 L232 A234 R237 R240 V241 K244
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0008097 5S rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:3jbp, PDBe:3jbp, PDBj:3jbp
PDBsum3jbp
PubMed26432834
UniProtQ8ILL3

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