Structure of PDB 8fmw Chain AQ Binding Site BS02

Receptor Information

>8fmw Chain AQ (length=119) Species: 224326 (Borreliella burgdorferi B31)

MKKIKEAEQRKLRRKKRIKDKIGRGVASRPRITVFKSNRYFYAQVIDDSK
GHTIASISTIEKSLNLGKNIDDVKKLGEVLAKRLKEKNINNLIFDRNGYK
YHGLIASFATSLREFGINI

Ligand information

>8fmw Chain AB (length=112)

cccuggugguuaaagaaaagaggaaacaccuguuaucauuccgaacacag
aaguuaagcucuuauucgcugaugguacugcgaguucgcgggagaguagg
uuauugccaggg

.<<<<<<<<.....<<.<<<<<.....<<<<<...............>>>
..>>....>>>>>..>><<<.......<<<<<....>>>>>.......>>
>..>>>>>>>>.

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8fmw The structure of a hibernating ribosome in a Lyme disease pathogen.
• Resolution: 2.86 Å
• Binding residue (original residue number in PDB): K19 R31 F35 K36 S37 N38 R39 Y40 Y42 Q44 G51 H52 T53 S56 K62 N69 I70 H102 L104
• Binding residue (residue number reindexed from 1): K19 R31 F35 K36 S37 N38 R39 Y40 Y42 Q44 G51 H52 T53 S56 K62 N69 I70 H102 L104

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0008097 5S rRNA binding
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8fmw, PDBe:8fmw, PDBj:8fmw
• PDBsum: 8fmw
• PubMed: 37907464
• UniProt: O51447|RL18_BORBU Large ribosomal subunit protein uL18 (Gene Name=rplR)