Structure of PDB 7tor Chain AL39 Binding Site BS02
Receptor Information
>7tor Chain AL39 (length=50) Species:
9986
(Oryctolagus cuniculus) [
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SSHKTFRIKRFLAKKQKQNRPIPQWIWMKTGNKIRYNSKRRHWRRTKLGL
Ligand information
>7tor Chain A58S (length=151) [
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cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcagguugaucaucgacacuucgaac
gcacuugcggccccggguuccucccggggcuacgccugucugagcgucgc
u
.........................................<<<<<<<<<
....>>>>.....<.<<<......>>........>>>..>...>>>....
<<<..>>><<<<<<<<.......>>>>>>>>...................
.
Receptor-Ligand Complex Structure
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PDB
7tor
Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.
Resolution
2.9 Å
Binding residue
(original residue number in PDB)
R8 K15 K18 Q19 R21 I23 P24 W26 I27 M29 T31 I35 K40
Binding residue
(residue number reindexed from 1)
R7 K14 K17 Q18 R20 I22 P23 W25 I26 M28 T30 I34 K39
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003735
structural constituent of ribosome
Biological Process
GO:0006412
translation
Cellular Component
GO:0005840
ribosome
GO:0022625
cytosolic large ribosomal subunit
GO:1990904
ribonucleoprotein complex
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Molecular Function
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Cellular Component
External links
PDB
RCSB:7tor
,
PDBe:7tor
,
PDBj:7tor
PDBsum
7tor
PubMed
35589706
UniProt
G1TTN1
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