Structure of PDB 4xej Chain AL18 Binding Site BS02

Receptor Information
>4xej Chain AL18 (length=98) Species: 262724 (Thermus thermophilus HB27) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLALKLKG
NKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAREG
Ligand information
>4xej Chain A5S (length=119) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ucccccgugcccauagcggcguggaaccacccguucccauuccgaacacg
gaagugaaacgcgccagcgccgaugguacugggcgggcgaccgccuggga
gaguaggucggugcggggg
.<<<<<<<<<.....<<<<<<<<....<<<<<<...............>>
>..>>>...>>>>>>.>><<<.......<<<<<<<<....>>>>>>>>..
.....>>>..>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB4xej Initiation of translation in bacteria by a structured eukaryotic IRES RNA.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		R15 K19 R25 F29 R30 S31 L32 K33 H34 Y36 Q38 G45 V46 T47 S50 G60 N61 K62 T63 Y92 H95 G96 R97
Binding residue
(residue number reindexed from 1)		R5 K9 R15 F19 R20 S21 L22 K23 H24 Y26 Q28 G35 V36 T37 S40 G50 N51 K52 T53 Y82 H85 G86 R87
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4xej, PDBe:4xej, PDBj:4xej
PDBsum4xej
PubMed25652826
UniProtQ72I20|RL18_THET2 Large ribosomal subunit protein uL18 (Gene Name=rplR)

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