Structure of PDB 6gz3 Chain AJ Binding Site BS02

Receptor Information

>6gz3 Chain AJ (length=169) Species: 9986 (Oryctolagus cuniculus)

ENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVR
SFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGFG
IQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRIS
KEEAMRWFQQKYDGIILPG

Ligand information

>6gz3 Chain A4 (length=119)

gucuacggccauaccacccugaacgcgcccgaucucgucugaucucggaa
gcuaagcagggucgggccugguuaguacuuggaugggagaccgccuggga
auaccgggugcuguaggcu

.<<<<<<<<....<<<<<<<<.....<<<<<..............>>>..
>>....>>>>>>.>><<<<<<<.....<<.<<..<<....>>.>>.>>..
..>>>>>>>>>>>>>>>..

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6gz3 tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis.
• Resolution: 3.6 Å
• Binding residue (original residue number in PDB): M12 Q46 T47 V49 T73 R75 P137 G138 S140 I141 K144 K145 R146 R147 C150 I151 A153 K154
• Binding residue (residue number reindexed from 1): M4 Q38 T39 V41 T65 R67 P129 G130 S132 I133 K136 K137 R138 R139 C142 I143 A145 K146

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005634 nucleus
• GO:0005730 nucleolus
• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6gz3, PDBe:6gz3, PDBj:6gz3
• PDBsum: 6gz3
• PubMed: 30517857
• UniProt: G1TUB8|RL11_RABIT Large ribosomal subunit protein uL5 (Gene Name=RPL11)