Structure of PDB 8hl4 Chain AEFG Binding Site BS02

Receptor Information
>8hl4 Chain AEFG (length=724) Species: 330779 (Sulfolobus acidocaldarius DSM 639) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VEQVLSLMKDVTRVRNIGIIAHVDHGKTTTSDTLLAASGIISQALALDYL
SVEQQRGITVKAANISLYHEIDGKGYVINLIDTPGHVDFSGRVTRSLRVL
DGSIVVIDAVEGIMTQTETVLRQSLEERVRPILFINKVDRLIKELKLSSQ
EIQKRLIDLIIEVNNLIETYGEPEFKDQWKIKPELGNVVFGSAKDKWGFS
VPMAGKRGVKFSDVVNAYTSGDKAKIEELASKVPIHEALLDAVIKFVPNP
RDSQKYRIPKIWKGDLDSEIAKAMINADPNGPIVMMINDMKVDPHAGLVA
TGRVFSGTLRAGEEVWLVNAKRQQRILQVSLYMGAIRELAEEIPVGNIAA
ALGMDAARSGETGVDIRFKDSVLGSFEKLHYISEPVVTISVEPRNPKDLT
KMIDALRKLSIEDSNLVVKINEETGEYLLSGMGFLHLEVSLQLLKENYGL
DVVTTPPIVVYRESIRNKSQVFEGKSPNKHNKLYISVEPLNNQTIDLIAN
GTIKEDMDNKEMAKILRDQAEWDYDEAKKIVAIDENINVFIDATSGVQHL
REIMDTLLQGFRLAMKEGPLAFEPVRGVKVVLHDAVVHEDPAHRGPAQLY
PAVRNAIFAGILTSKPTLLEPLQKLDIRIPMEYLGNVTAVITRKRGKVIN
VVQTGNVARVYAEIPVGESFELASELRASSAGRAFWGTEFSRWAPVPDSI
LVDLIMKIRERKGKPKQLPKVEDF
Ligand information
>8hl4 Chain A16S (length=1492) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auuccgguugauccugccggacccgaccgcuaucgggguagggauaagcc
augggagucuuacacucccggguaagggaguguggcggacggcugaguaa
cacguggcuaaccuacccucgggacggggauaaccccgggaaacugggga
uaauccccgauagggaaggaguccuggaaugguuccuucccuaaagggcu
auaggcuauuucccguuuguagccgcccgaggauggggcuacggcccauc
aggcugucggugggguaaaggcccaccgaaccuauaacggguaggggccg
uggaagcgggagccuccaguugggcacugagacaagggcccaggcccuac
ggggcgcaccaggcgcgaaacguccccaaugcgcgaaagcgugagggcgc
uaccccgagugccuccgcaggaggcuuuuccccgcucuaaaaaggcgggg
gaauaagcggggggcaagucuggugucagccgccgcgguaauaccagcuc
cgcgaguggucggggugauuacugggccuaaagcgccuguagccggccca
ccaagucgccccuuaaaguccccggcucaaccggggaacugggggcgaua
cuggugggcuagggggcgggagaggcgggggguacucccggaguaggggc
gaaauccuuagauaccgggaggaccaccaguggcggaagcgccccgcuag
aacgcgcccgacggugagaggcgaaagccggggcagcaaacgggauuaga
uaccccgguagucccggcuguaaacgaugcgggcuaggugucgaguaggc
uuagagccuacucggugccgcagggaagccguuaagcccgccgccugggg
aguacggucgcaagacugaaacuuaaaggaauuggcgggggagcaccaca
agggguggaaccugcggcucaauuggagucaacgccuggaaucuuaccgg
gggagaccgcaguaugacggccaggcuaacgaccuugccugacucgcgga
gaggaggugcauggccgucgccagcucguguugugaaauguccgguuaag
uccggcaacgagcgagacccccaccccuaguugguauucuggacuccggu
ccagaaccacacuagggggacugccggcguaagccggaggaaggaggggg
ccacggcaggucagcaugccccgaaacucccgggccgcacgcggguuaca
auggcagggacaacgggaugcuaccucaaagggggagccaauccuuaaac
ccugccgcaguugggaucgagggcugaaacccgcccucgugaacgaggaa
ucccuaguaaccgcgggucaacaacccgcggugaauacgucccugcuccu
ugcacacaccgcccgucgcuccacccgagcgagaaaggggugaggucccu
ugcgauaagugggggaucgaacuccuuucccgcgaggggggagaagucgu
aacaagguagccguaggggaaccugcggcuggaucaccucau
...<<<<<.[.((((>>>>>.<<<<<<<<<.....<<<.<<......<<<
.<<<..<<<..<<<<<<<<......>>>>>>>>>>>......<<......
..<<<<<<<..<<...<<<<<<<.<<<<<....<<<<<......>>>>>.
....>>>>>..<<<<<<<<<<.<<......>>>>>>>>>>>>...<.<<<
<<<..............>>>>>>>.>>>>>>>..>>>>>>>>>.<<<...
.<<...<<<<<<<<.......>>>>>>>>.>>......>>>..<<<<<<<
<....>>>>...>>>>.>>.<<<<<............>>>>>.<<<<...
.>>>>...>>>>>>.........<<<....<<<<....>>>>..>>>..>
>..>>>....<<<<<<...>>>>>>...<<<<<<<.........>>>>>>
>.....<<<<<((......<<<<.....<<..))>>.......>>>>.>>
>>>..>>>>>>>>>..........<<<((.....<<<<...<<<.<<<<<
<<.<<<<<<<<<......<<<<<<<.....>>>>>>>....>>>>>>>..
>>>>>>>>>...<<<<<<.....<<<<<<<<<<.<<<<<<<....<<<..
....>>>.......>>>>>>>.>>>.......<<....>>.>>>>>>>..
..>>>.>>>...>>>...>>>>...<<<<<<<...<<...<<<<.<....
.>.>>>>...>>>>>>>>>.........<<<<<<..<<<<<<<<<<<<<<
.....>>>>>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<.
.....<<<<....>>>>....>>>..)))).]<<<<<.<<<<<<<..<<.
<<<<<<..<<<<<<<<<<......<<........>>..........<<<<
<.<...<<<<........<<<.<<<.......>>>.>>>......>>>>.
..<<.<<<..<<<<<<<<.....<<<<<<<<<....>>>..<<<<.....
.>>>>..>>>>>>....<<<<<.<<<<<<<.<<<..<<<<<<<<....>>
>>>>>>>>..>>>>>>>>.....<<<<<....>>>>>........>>>>>
.....>>.>>>...>>>>>>>>.....>>>>>>...>>.>>>>>>>>...
..<<<<<<<.....<<...<<..<<<.....>>>..>>....>>.....>
>>>>>>......<....<<<<<<<........>>>>>>>....>.....>
>>>>>....<<<<<<<<.......>>>>>>>>......>>...>>>>>>>
>>>.>>....<..<<.<.<<<<.<<<..<<<.<<<<<<<<<..<<<<<<<
<<<.....>>>>>>>>>>..>>>>>>>>>.>>>..>>>.>>>>..>.>>.
..>.....<<<<<<<<<....>>>>>>>>>............
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8hl4 Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome
Resolution4.62 Å
Binding residue
(original residue number in PDB)		K521 Q559
Binding residue
(residue number reindexed from 1)		K510 Q548
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8hl4, PDBe:8hl4, PDBj:8hl4
PDBsum8hl4
PubMed37604686
UniProtP23112|EF2_SULAC Elongation factor 2 (Gene Name=fusA)

[Back to BioLiP]