Structure of PDB 7qi6 Chain AE Binding Site BS02

Receptor Information

>7qi6 Chain AE (length=122) Species: 9606 (Homo sapiens)

PRYELALILKAMQRPETAATLKRTIEALMDRGAIVRDLENLGERALPYRI
SAHSQQHNRGGYFLVDFYAPTAAVESMVEHLSRDIDVIRGNIVKHPLTQE
LKECEGIVPVPLAEKLYSTKKR

Ligand information

• Ligand ID: FES
• InChI: InChI=1S/2Fe.2S
• InChIKey: NIXDOXVAJZFRNF-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04: [Fe]1S[Fe]S1
  CACTVS 3.341
  OpenEye OEToolkits 1.5.0: S1[Fe]S[Fe]1
• Formula: Fe2 S2
• Name: FE2/S2 (INORGANIC) CLUSTER
• PDB chain: 7qi6 Chain AP Residue 201

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7qi6 Structure of mitoribosome reveals mechanism of mRNA binding, tRNA interactions with L1 stalk, roles of cofactors and rRNA modifications.
• Resolution: 2.98 Å
• Binding residue (original residue number in PDB): C105 G107
• Binding residue (residue number reindexed from 1): C104 G106
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0005515 protein binding
• GO:0019843 rRNA binding
• GO:0070181 small ribosomal subunit rRNA binding

Biological Process

• GO:0006412 translation
• GO:0032543 mitochondrial translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005739 mitochondrion
• GO:0005743 mitochondrial inner membrane
• GO:0005763 mitochondrial small ribosomal subunit
• GO:0005840 ribosome
• GO:0015935 small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7qi6, PDBe:7qi6, PDBj:7qi6
• PDBsum: 7qi6
• PubMed: 38769321
• UniProt: P82932|RT06_HUMAN Small ribosomal subunit protein bS6m (Gene Name=MRPS6)