Structure of PDB 8bq5 Chain AD Binding Site BS02

Receptor Information

>8bq5 Chain AD (length=196) Species: 3702 (Arabidopsis thaliana)

EVPATVEAVKTPNSKIVYDDHNHERYPPGDPSKRAFAYFVLSGGRFVYAS
VLRLLVLKLIVSMSASKDVLALASLEVDLGSIEPGTTVTVKWRGKPVFIR
RRTEDDIKLANSVDVGSLRDPQEDSVRVKNPEWLVVVGVCTHLGCIPLPN
AGDYGGWFCPCHGSHYDISGRIRKGPAPYNLEVPTYSFLEENKLLI

Ligand information

• Ligand ID: FES
• InChI: InChI=1S/2Fe.2S
• InChIKey: NIXDOXVAJZFRNF-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04: [Fe]1S[Fe]S1
  CACTVS 3.341
  OpenEye OEToolkits 1.5.0: S1[Fe]S[Fe]1
• Formula: Fe2 S2
• Name: FE2/S2 (INORGANIC) CLUSTER
• PDB chain: 8bq5 Chain AD Residue 301

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8bq5 Cryo-EM structure of the respiratory I + III 2 supercomplex from Arabidopsis thaliana at 2 angstrom resolution.
• Resolution: 2.73 Å
• Binding residue (original residue number in PDB): C215 H217 L218 C220 C234 C236 H237 S239
• Binding residue (residue number reindexed from 1): C140 H142 L143 C145 C159 C161 H162 S164
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 7.1.1.8: quinol--cytochrome-c reductase.

Gene Ontology

Molecular Function

• GO:0008121 ubiquinol-cytochrome-c reductase activity
• GO:0046872 metal ion binding
• GO:0051537 2 iron, 2 sulfur cluster binding

Biological Process

• GO:1902600 proton transmembrane transport

Cellular Component

• GO:0005739 mitochondrion
• GO:0005743 mitochondrial inner membrane
• GO:0009536 plastid
• GO:0016020 membrane
• GO:0031966 mitochondrial membrane
• GO:0045275 respiratory chain complex III

External links

• PDB: RCSB:8bq5, PDBe:8bq5, PDBj:8bq5
• PDBsum: 8bq5
• PubMed: 36585502
• UniProt: Q94JS0|UCRI1_ARATH Cytochrome b-c1 complex subunit Rieske-1, mitochondrial (Gene Name=UCR1-1)