Structure of PDB 8pte Chain AAA Binding Site BS02

Receptor Information

>8pte Chain AAA (length=129) Species: 9031 (Gallus gallus)

KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGS
TDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVS
DGNGMNAWVAWRNRCKGTDVQAWIRGCRL

Ligand information

• Ligand ID: H1W
• InChI: InChI=1S/5H2O.V/h5*1H2;/q;;;;;+5/p-5
• InChIKey: QKDGGEBMABOMMW-UHFFFAOYSA-I
• SMILES:
  CACTVS 3.385
  OpenEye OEToolkits 2.0.6: O[V](O)(O)(O)O
• Formula: H5 O5 V
• Name: pentakis(oxidanyl)vanadium
• PDB chain: 8pte Chain AAA Residue 203

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8pte Stabilization and Binding of [V 4 O 12 ] 4- and Unprecedented [V 20 O 54 (NO 3 )] n- to Lysozyme upon Loss of Ligands and Oxidation of the Potential Drug V IV O(acetylacetonato) 2.
• Resolution: 1.797 Å
• Binding residue (original residue number in PDB): E35 N46 D52 Q57
• Binding residue (residue number reindexed from 1): E35 N46 D52 Q57
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 3.2.1.17: lysozyme.

Gene Ontology

Molecular Function

• GO:0003796 lysozyme activity
• GO:0005515 protein binding
• GO:0016231 beta-N-acetylglucosaminidase activity
• GO:0016798 hydrolase activity, acting on glycosyl bonds
• GO:0042802 identical protein binding

Biological Process

• GO:0016998 cell wall macromolecule catabolic process
• GO:0031640 killing of cells of another organism
• GO:0042742 defense response to bacterium
• GO:0050829 defense response to Gram-negative bacterium
• GO:0050830 defense response to Gram-positive bacterium

Cellular Component

• GO:0005576 extracellular region
• GO:0005615 extracellular space
• GO:0005737 cytoplasm
• GO:0005783 endoplasmic reticulum

External links

• PDB: RCSB:8pte, PDBe:8pte, PDBj:8pte
• PDBsum: 8pte
• PubMed: 37768728
• UniProt: P00698|LYSC_CHICK Lysozyme C (Gene Name=LYZ)