Structure of PDB 8omt Chain AAA Binding Site BS02

Receptor Information
>8omt Chain AAA (length=129) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGS
TDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVS
DGNGMNAWVAWRNRCKGTDVQAWIRGCRL
Ligand information
Ligand IDVTZ
InChIInChI=1S/C8H11NO2.4O.V/c1-3-6-8(11)7(10)4-5-9(6)2;;;;;/h4-5,11H,3H2,1-2H3;;;;;/q;;3*-1;+4/p-1
InChIKeyPNFKDCNTOXLWCD-UHFFFAOYSA-M
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7CCC1=C2C(=[O-][V+4](=O)(O2)([O-])([O-])[O-])C=CN1C
CACTVS 3.385CCC1=C2O[V+4]([O-])([O-])([O-])(=O)[O-]=C2C=CN1C
FormulaC8 H10 N O6 V
Name1-methyl-2-ethyl-3-hydroxy-4(1H)-pyridinone)V(IV)O4
ChEMBL
DrugBank
ZINC
PDB chain8omt Chain AAA Residue 204 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8omt Implications of Protein Interaction in the Speciation of Potential V IV O-Pyridinone Drugs.
Resolution1.097 Å
Binding residue
(original residue number in PDB)		R5 W123 R125
Binding residue
(residue number reindexed from 1)		R5 W123 R125
Annotation score1
Enzymatic activity
Enzyme Commision number 3.2.1.17: lysozyme.
Gene Ontology
Molecular Function
GO:0003796 lysozyme activity
GO:0005515 protein binding
GO:0016231 beta-N-acetylglucosaminidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0042802 identical protein binding
Biological Process
GO:0016998 cell wall macromolecule catabolic process
GO:0031640 killing of cells of another organism
GO:0042742 defense response to bacterium
GO:0050829 defense response to Gram-negative bacterium
GO:0050830 defense response to Gram-positive bacterium
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8omt, PDBe:8omt, PDBj:8omt
PDBsum8omt
PubMed37195003
UniProtP00698|LYSC_CHICK Lysozyme C (Gene Name=LYZ)

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