Structure of PDB 8om8 Chain AAA Binding Site BS02

Receptor Information
>8om8 Chain AAA (length=129) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGS
TDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVS
DGNGMNAWVAWRNRCKGTDVQAWIRGCRL
Ligand information
Ligand IDVTZ
InChIInChI=1S/C8H11NO2.4O.V/c1-3-6-8(11)7(10)4-5-9(6)2;;;;;/h4-5,11H,3H2,1-2H3;;;;;/q;;3*-1;+4/p-1
InChIKeyPNFKDCNTOXLWCD-UHFFFAOYSA-M
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7CCC1=C2C(=[O-][V+4](=O)(O2)([O-])([O-])[O-])C=CN1C
CACTVS 3.385CCC1=C2O[V+4]([O-])([O-])([O-])(=O)[O-]=C2C=CN1C
FormulaC8 H10 N O6 V
Name1-methyl-2-ethyl-3-hydroxy-4(1H)-pyridinone)V(IV)O4
ChEMBL
DrugBank
ZINC
PDB chain8om8 Chain AAA Residue 203 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8om8 Implications of Protein Interaction in the Speciation of Potential V IV O-Pyridinone Drugs.
Resolution1.08 Å
Binding residue
(original residue number in PDB)		N46 D48 S50 N59 R61
Binding residue
(residue number reindexed from 1)		N46 D48 S50 N59 R61
Annotation score1
Enzymatic activity
Enzyme Commision number 3.2.1.17: lysozyme.
Gene Ontology
Molecular Function
GO:0003796 lysozyme activity
GO:0005515 protein binding
GO:0016231 beta-N-acetylglucosaminidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0042802 identical protein binding
Biological Process
GO:0016998 cell wall macromolecule catabolic process
GO:0031640 killing of cells of another organism
GO:0042742 defense response to bacterium
GO:0050829 defense response to Gram-negative bacterium
GO:0050830 defense response to Gram-positive bacterium
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8om8, PDBe:8om8, PDBj:8om8
PDBsum8om8
PubMed37195003
UniProtP00698|LYSC_CHICK Lysozyme C (Gene Name=LYZ)

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