Structure of PDB 8oh8 Chain AAA Binding Site BS02

Receptor Information
>8oh8 Chain AAA (length=298) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VTIKDIEVLNCEYGKNTIKFLRLHREGKKHFVKEVEVCTHLRLTSAHEYL
DGNNSFVIPTDTIKNIVLVLAKKNGISSIEQFAIDICKHFMTTFCQVAYV
KTYIQEVPWQRQYQNGVPHIHSFILVPDGIRFCEAEQCRNGPLVVCAGIK
DLKLMKTTQSGFEGFYRNEHTTLPERNDRILCGEFFCKWSYGECRDFDFD
CIWSKVRECILEAFSGPPDCGEYSPSYQRTVNCIQMCVLSRVPQVQVIEV
ILNNNFYNVVDMKALGCTNDKEVLVPVETPYGSCACTLGRKKYLEAQS
Ligand information
Ligand IDOXY
InChIInChI=1S/O2/c1-2
InChIKeyMYMOFIZGZYHOMD-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341
OpenEye OEToolkits 1.5.0		O=O
FormulaO2
NameOXYGEN MOLECULE
ChEMBLCHEMBL1234886
DrugBankDB09140
ZINC
PDB chain8oh8 Chain BBB Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8oh8 Cysteine Enrichment Mediates Co-Option of Uricase in Reptilian Skin and Transition to Uricotelism.
Resolution2.12 Å
Binding residue
(original residue number in PDB)		N257 G285
Binding residue
(residue number reindexed from 1)		N254 G282
Annotation score5
Enzymatic activity
Enzyme Commision number 1.7.3.3: factor independent urate hydroxylase.
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
Biological Process
GO:0006144 purine nucleobase metabolic process
Cellular Component
GO:0005777 peroxisome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8oh8, PDBe:8oh8, PDBj:8oh8
PDBsum8oh8
PubMed37695804
UniProtA0A8V0ZED1

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