Structure of PDB 8aj5 Chain AAA Binding Site BS02

Receptor Information

>8aj5 Chain AAA (length=129) Species: 9031 (Gallus gallus)

KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGS
TDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVS
DGNGMNAWVAWRNRCKGTDVQAWIRGCRL

Ligand information

• Ligand ID: VVB
• InChI: InChI=1S/2H2O.V/h2*1H2;/q;;+2/p-2
• InChIKey: UVEFAEMXFFXFKB-UHFFFAOYSA-L
• SMILES:
  CACTVS 3.385
  OpenEye OEToolkits 2.0.7: O[V]O
• Formula: H2 O2 V
• Name: bis(oxidanyl)vanadium
• PDB chain: 8aj5 Chain AAA Residue 206

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8aj5 Multiple and Variable Binding of Pharmacologically Active Bis(maltolato)oxidovanadium(IV) to Lysozyme.
• Resolution: 1.31 Å
• Binding residue (original residue number in PDB): A10 L129
• Binding residue (residue number reindexed from 1): A10 L129
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 3.2.1.17: lysozyme.

Gene Ontology

Molecular Function

• GO:0003796 lysozyme activity
• GO:0005515 protein binding
• GO:0016231 beta-N-acetylglucosaminidase activity
• GO:0016798 hydrolase activity, acting on glycosyl bonds
• GO:0042802 identical protein binding

Biological Process

• GO:0016998 cell wall macromolecule catabolic process
• GO:0031640 killing of cells of another organism
• GO:0042742 defense response to bacterium
• GO:0050829 defense response to Gram-negative bacterium
• GO:0050830 defense response to Gram-positive bacterium

Cellular Component

• GO:0005576 extracellular region
• GO:0005615 extracellular space
• GO:0005737 cytoplasm
• GO:0005783 endoplasmic reticulum

External links

• PDB: RCSB:8aj5, PDBe:8aj5, PDBj:8aj5
• PDBsum: 8aj5
• PubMed: 36205235
• UniProt: P00698|LYSC_CHICK Lysozyme C (Gene Name=LYZ)