Structure of PDB 6sgg Chain AAA Binding Site BS02

Receptor Information
>6sgg Chain AAA (length=337) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDFALSMIK
LRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARM
AATIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQV
LRDLWGTGKSDFKGDFFTMNDCRVSPQPSVPMKVICAGQSDAGMAFSARY
ADFNFCFGKGVNTPTAFAPTAARMKQAAEQTGRDVGSYVLFMVIADETDD
AARAKWEHYKAGADEEALSWLTDPTSAVNINMGTLVGSYASVARMLDEVA
SVPGAEGVLLTFDDFLSGIETFGERIQPLMQCRAHLP
Ligand information
Ligand IDOXY
InChIInChI=1S/O2/c1-2
InChIKeyMYMOFIZGZYHOMD-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341
OpenEye OEToolkits 1.5.0		O=O
FormulaO2
NameOXYGEN MOLECULE
ChEMBLCHEMBL1234886
DrugBankDB09140
ZINC
PDB chain6sgg Chain AAA Residue 404 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6sgg Aminoperoxide adducts expand the catalytic repertoire of flavin monooxygenases.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		M67 N134
Binding residue
(residue number reindexed from 1)		M48 N115
Annotation score5
Enzymatic activity
Enzyme Commision number 1.14.99.46: pyrimidine monooxygenase.
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0008726 alkanesulfonate monooxygenase activity
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0052614 uracil oxygenase activity
Biological Process
GO:0006208 pyrimidine nucleobase catabolic process
GO:0006210 thymine catabolic process
GO:0006212 uracil catabolic process
GO:0019740 nitrogen utilization
GO:0046306 alkanesulfonate catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6sgg, PDBe:6sgg, PDBj:6sgg
PDBsum6sgg
PubMed32066967
UniProtP75898|RUTA_ECOLI Pyrimidine monooxygenase RutA (Gene Name=rutA)

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