Structure of PDB 5e81 Chain A8 Binding Site BS02

Receptor Information
>5e81 Chain A8 (length=111) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ARLTAYERRKFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSA
SSLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKAL
AEGAREGGLEF
Ligand information
>5e81 Chain 16 (length=122) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaucccccgugcccauagcggcguggaaccacccguucccauuccgaaca
cggaagugaaacgcgccagcgccgaugguacugggcgggcgaccgccugg
gagaguaggucggugcggggga
..<<<<<<<<<<<....<<<<<<<<....<<<<<<...............
>>>..>>>...>>>>>>.>><<<.......<<<<<<<<....>>>>>>>>
.......>>>.>>>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB5e81 Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code.
Resolution2.95 Å
Binding residue
(original residue number in PDB)		R15 R25 F29 R30 S31 L32 K33 H34 Y36 Q38 G45 S50 L54 A55 N61 K62 T63 Y92 K93 H95 G96 R97
Binding residue
(residue number reindexed from 1)		R14 R24 F28 R29 S30 L31 K32 H33 Y35 Q37 G44 S49 L53 A54 N60 K61 T62 Y91 K92 H94 G95 R96
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0008097 5S rRNA binding
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5e81, PDBe:5e81, PDBj:5e81
PDBsum5e81
PubMed26791911
UniProtQ5SHQ4|RL18_THET8 Large ribosomal subunit protein uL18 (Gene Name=rplR)

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