Structure of PDB 7tbm Chain A4 Binding Site BS02

Receptor Information

>7tbm Chain A4 (length=1269) Species: 9606 (Homo sapiens)

DLPPVAKAAQVVNQTLQLDDSYPDLDSYCRPGASSDYEMQSSDSSWAPFH
VVRHHNIPDKVFEHLNAGEVFTKLGLFAEIGYAWASIDSSLFLWDYTHPN
PELIGYEEATHTITAVALVPPKPGVFVKTITHVLVVATTSEIILLGVSAT
PTPSGSKSLTLYSTRMSVHRGGSDVSFIVGTKDGRIFLGGESDTDIHEIF
YQQEERWFSSRCGKINHSHPFGSRQQEWLRGLYVDDTRNLLYSLSNRSTI
RTYHMEGPEKLTKVIEKDKTSCLRDFAHMADSSPLFTDKTNIVALSPIPA
TEASKLHLMALTDTGCRLFLSATSSALAPQSMQLQFVKFPPRESPTRIRT
LNSQLDKTSRALDPSALGFRFSPGYFFDVVRKHPNQDMLFVSAPDTGRIK
VTQPASALKYFEQGTWIELENGNRTIEIGLTTAPFAAAKQPLGFGNELAV
QFDQVPGEFAVLTNTGVHIVRRRRLVDIFAKALGNCVSASDDALEREVRK
FINQYGRVETIAAALAVACGQGSMDRNTENLARAAFIEYGGQPRLAAESV
RLSSRHDALALYLTRLVRTLWKAKVVQVGSGSDISSTIPTLVTIQENVER
LRNFLEANKSTIQGLAPPEDIANQKEHQALHALQKLMESISEGISFVLML
FDERVSDIYARLDAVSQQQLKDLTYEQLFSQTPGKELAKVLVKAIVNRNI
AAPDDVVTFKAQEQLQRASEQAHNAPVLRALLAESLRLFEQVAGSLTPAN
LTTAVEQMISLKYYAGAIQLCLTVAQQKDRGNTALSWVNDGKPANDSRKK
AFDERKICYNLIHQVLDKLESDFAGEPELVDGRPTLAATKRMEAYNVVND
SSDEVFHFDMYEWYIEKGWTDRILSIDSPHVITYLQRLAETDFRHAELLC
RFYTTRSRFFEAAQVQTNLAKSDLNISLKDRIILLSRAKGNASVNTIGIS
RQQQQQLNHEASELLEIAHIQDDLLERLVADPRIPEERKAEIEEFLDGPI
RTLTDLFNDYADQANYYDLCLLIFHAADFHNPRTIMDTWNNLINQSHFEA
EQRREYWEIVQAGGDLPAGVIAPIAEPPLPYVYVSQQIQLIAHRTSLDSL
IFPVNSLLPVVCAYAINNGQDASIGADPCWPIQLFLNLGVPHALMVQVLE
NVLDTQEAPFTGRRRKLVVQWIAMAVDMWVREVERRGAMAAAAASGASGS
EAVMGSWVSELLGRADQVLTQIAGTGATLRGGAASDAEEIASLRRTVKGL
KRSVDMLLGGEMARMSFFR

Ligand information

>7tbm Chain B6 (length=14) Species: 9606 (Homo sapiens)

RKAKLLPMEEALLP

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7tbm Architecture of the cytoplasmic face of the nuclear pore.
• Resolution: 37.0 Å
• Binding residue (original residue number in PDB): P895 L898 T899 V902 G913 A914 I915 Q916 L917 C918 W934 P940 N942 D943 S944 R945 K946 K947 A948 F949 D950 E951 R952 K953 I954 C955 L958 Q961
• Binding residue (residue number reindexed from 1): P748 L751 T752 V755 G766 A767 I768 Q769 L770 C771 W787 P793 N795 D796 S797 R798 K799 K800 A801 F802 D803 E804 R805 K806 I807 C808 L811 Q814

Gene Ontology

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UnboundLocalError

Python 3.6.8: /usr/bin/python3 Fri Nov 22 16:53:52 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1435     title=pdb2title(pdbid)

   1436     if bs.startswith("BS"):

=> 1437         pubmed,uniprot=display_interaction(pdbid,asym_id,bs,title)

   1438     else:

   1439         if lig3:

pubmed = '', uniprot = '', display_interaction = <function display_interaction>, pdbid = '7tbm', asym_id = 'A4', bs = 'BS02', title = 'Architecture of the cytoplasmic face of the nuclear pore.'

 /var/www/html/BioLiP/pdb.cgi in display_interaction(pdbid='7tbm', asym_id='A4', bs='BS02', title='Architecture of the cytoplasmic face of the nuclear pore.')

   1295         display_ec(ec,csaOrig,csaRenu)

   1296     if go:

=> 1297         display_go(go,uniprot,pdbid,asym_id)

   1298     return pubmed,uniprot

   1299 

global display_go = <function display_go>, go = '0005643,0006913,0017056', uniprot = '', pdbid = '7tbm', asym_id = 'A4'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0005643,0006913,0017056', uniprot='', pdbid='7tbm', asym_id='A4')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>