Structure of PDB 9f37 Chain A Binding Site BS02

Receptor Information
>9f37 Chain A (length=703) Species: 11320 (Influenza A virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MENFVRTNFNPMILERAEKTMKEYGENPQNEGNKFAAISTHMEVCFMYSD
FHFIDLEGNTIVKENMLKHRFEIIEGQERNIAWTIVNSICNMTENSKPRF
LPDLYDYKTNKFIEIGVTRRKVEDYYYEKASKLKGENVYIHIFSFDGEEM
ATDDEYILDEESRARIKTRLFVLRQELATAGLWDSFRQSTLEEEFSYPPT
FQRLANQSLPPSFKDYHQFKAYVSSFKANGNIEAKLGAMSEKVNAQIESF
DPRTIRELELPEGKFCTQRSKFLLMDAMKLSVLNPAHEGEGIPMKDAKAC
LDTFWGWKKATIIKKHEKGVNTNYLMIWEQLLESIKEMEGKFLNLKKTNH
LKWGLGEGQAPEKMDFEDCKEVPDLFQYKSEPPEKRKLASWIQSEFNKAS
ELTNSNWIEFDELGNDVAPIEHIASRRRNFFTAEVSQCRASEYIMKAVYI
NTALLNSSCTAMEEYQVIPIITKCRDTSGQRRTNLYGFIIKGRSHLRNDT
DVVNFISLEFSLTDPRNEIHKWEKYCVLEIGDMEIRTSISTIMKPVYLYV
RTNGTSKIKMKWGMEMRRCLLQSLQQVESMIEAESAVKEKDMTEPFFRNR
ENDWPIGESPQGIEKGTIGKVCRVLLAKSVFNSIYASAQLEGFSAESRKL
LLLIQAFRDNLDPGTFDLKGLYEAIEECIINDPWVLLNASWFNSFLKAVQ
LSM
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9f37 High-resolution structure of a replication-initiation like configuration of influenza polymerase active site visualises the essential role of a conserved dibasic motif in the PA subunit
Resolution1.905 Å
Binding residue
(original residue number in PDB)
K281 H326 K328 G366 G368 Q369 A370 P371 Y388 K389 S390 P392 P393 R503 H505 D511 V512 N514 K534 R561 T562 N563 G564
Binding residue
(residue number reindexed from 1)
K271 H316 K318 G356 G358 Q359 A360 P361 Y378 K379 S380 P382 P383 R493 H495 D501 V502 N504 K524 R551 T552 N553 G554
External links