Structure of PDB 9f2r Chain A Binding Site BS02

Receptor Information
>9f2r Chain A (length=708) Species: 11320 (Influenza A virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMENFVRTNFNPMILERAEKTMKEYGENPQNEGNKFAAISTHMEVCFMYS
DFHFIDLEGNTIVKENDDAMLKHRFEIIEGQERNIAWTIVNSICNMTENS
KPRFLPDLYDYKTNKFIEIGVTRRKVEDYYYEKASKLKGENVYIHIFSFD
GEEMATDDEYILDEESRARIKTRLFVLRQELATAGLWDSFRQSELEEEFS
YPPTFQRLANQSLPPSFKDYHQFKAYVSSFKANGNIEAKLGAMSEKVNAQ
IESFDPRTIRELELPEGKFCTQRSKFLLMDAMKLSVLNPAHEGEGIPMKD
AKACLDTFWGWKKATIIKKHEKGVNTNYLMIWEQLLESIKEMEGKFLNLK
KTNHLKWGLGEGQAPEKMDFEDCKEVPDLFQYKSEPPEKRKLASWIQSEF
NKASELTNSNWIEFDELGNDVAPIEHIASRRRNFFTAEVSQCRASEYIMK
AVYINTALLNSSCTAMEEYQVIPIITKCRDTSGQRRTNLYGFIIKGRSHL
RNDTDVVNFISLEFSLTDPRNEIHKWEKYCVLEIGDMEIRTSISTIMKPV
YLYVRTNGTSKIKMKWGMEMRRCLLQSLQQVESMIEAESAVKEKDMTEPF
FRNRENDWPIGESPQGIEKGTIGKVCRVLLAKSVFNSIYASAQLEGFSAE
SRKLLLLIQAFRDNLDPGTFDLKGLYEAIEECIINDPWVLLNASWFNSFL
KAVQLSMG
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9f2r High-resolution structure of a replication-initiation like configuration of influenza polymerase active site visualises the essential role of a conserved dibasic motif in the PA subunit
Resolution1.959 Å
Binding residue
(original residue number in PDB)
K281 H326 K328 W363 G366 G368 Q369 A370 P371 K373 Y388 K389 S390 P392 P393 R503 H505 V512 N514 K534 R561 T562 N563 G564 K569
Binding residue
(residue number reindexed from 1)
K275 H320 K322 W357 G360 G362 Q363 A364 P365 K367 Y382 K383 S384 P386 P387 R497 H499 V506 N508 K528 R555 T556 N557 G558 K563
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