Structure of PDB 9eqf Chain A Binding Site BS02

Receptor Information
>9eqf Chain A (length=335) Species: 32630 (synthetic construct) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RPWSEFRLTPAEAAAAAALAARCAQRYDETDGPEFLLDAPVIAHELPRRL
RTFMARARLDAWPHALVVRGNPVDDAALGSTPVHWRTARTPGSRPLSFLL
MLYAGLLGDVFGWATQQDGRVVTDVLPIKGGEHTLVSSSSRQELGWHTED
AFSPYRADYVGLLSLRNPDGVATTLAGVPLDDLDERTLDVLFQERFLIRP
DDSHLQVNNSTAQQGRVEFEGIAQAADRPEPVAILTGHRAAPHLRVDGDF
SAPAEGDEEAAAALGTLRKLIDASLYELVLDQGDVAFIDNRRAVHGRRAF
QPRYDGRDRWLKRINITRDLHRSRKAWASRVLGQR
Ligand information
Ligand IDARG
InChIInChI=1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/p+1/t4-/m0/s1
InChIKeyODKSFYDXXFIFQN-BYPYZUCNSA-O
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(CC(C(=O)O)N)CNC(=[NH2+])N
CACTVS 3.341N[C@@H](CCCNC(N)=[NH2+])C(O)=O
OpenEye OEToolkits 1.5.0C(C[C@@H](C(=O)O)N)CNC(=[NH2+])N
CACTVS 3.341N[CH](CCCNC(N)=[NH2+])C(O)=O
ACDLabs 10.04O=C(O)C(N)CCCN\C(=[NH2+])N
FormulaC6 H15 N4 O2
NameARGININE
ChEMBL
DrugBank
ZINC
PDB chain9eqf Chain A Residue 403 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB9eqf Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
Resolution1.6 Å
Binding residue
(original residue number in PDB)		L156 V157 S158 L165 H168 E170 D222 S224 D268 D270 F271 R334
Binding residue
(residue number reindexed from 1)		L135 V136 S137 L144 H147 E149 D201 S203 D247 D249 F250 R313
Annotation score5
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0016706 2-oxoglutarate-dependent dioxygenase activity
GO:0046872 metal ion binding
GO:0102525 2-oxoglutarate, L-arginine oxygenase (succinate-forming) activity
Biological Process
GO:0017000 antibiotic biosynthetic process
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:9eqf, PDBe:9eqf, PDBj:9eqf
PDBsum9eqf
PubMed39114090
UniProtQ6WZB0|ARGHX_STRVI Alpha-ketoglutarate-dependent L-arginine hydroxylase (Gene Name=vioC)

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