Structure of PDB 9bs4 Chain A Binding Site BS02

Receptor Information

>9bs4 Chain A (length=627) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

DPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVET
LSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLALGVGDGVLLKAVAQA
TGRQLESVRAEAAEKGDVGLVAENSRPPPPLTASGVFSKFRDIARLTGSA
STAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVS
LTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIP
VLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYK
YDGQRAQIHALEGGEVKIFSRNQADNTGKYPDIISRIPKIKLPSVTSFIL
DTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGE
SLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDS
CEGLMVKTLDVDATYEIAKRSHNWLKLKKDYDTLDLVVIGAYLGRGKRAG
RYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPY
VRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFP
RFIRVREDKQPEQATTSAQVACLYRKQ

Ligand information

>9bs4 Chain C (length=7) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

gtcggac

Receptor-Ligand Complex Structure

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Structure summary

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PDB	9bs4 Structures of LIG1 uncover the mechanism of sugar discrimination against 5'-RNA-DNA junctions during ribonucleotide excision repair.
Resolution	2.4 Å
Binding residue (original residue number in PDB)	A304 R589 R738 K744 T798 G799 F872
Binding residue (residue number reindexed from 1)	A43 R321 R470 K476 T525 G526 F599

External links

PDB	RCSB:9bs4, PDBe:9bs4, PDBj:9bs4
PDBsum	9bs4
PubMed	39159820
UniProt	P18858\|DNLI1_HUMAN DNA ligase 1 (Gene Name=LIG1)

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