Structure of PDB 9bh9 Chain A Binding Site BS02

Receptor Information
>9bh9 Chain A (length=787) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLLLANWGLPKAVLEKYHSFGVKKMFEWQAECLLLGQVLEGKNLVYSAPT
SAGKTLVAELLILKRVLEMRKKALFILPFVSVAKEKKYYLQSLFQEVGIK
VDGYMGSTSPSRHFSSLDIAVCTIERANGLINRLIEENKMDLLGMVVVDE
LHMLGDSHRGYLLELLLTKICYITRKSASSNAVQIVGMSATLPNLELVAS
WLNAELYHTDFRPVPLLESVKVGNSIYDSSMKLVREFEPMLQVKGDEDHV
VSLCYETICDNHSVLLFCPSKKWCEKLADIIAREFYNLHHQACPPVILEQ
KELLEVMDQLRRLPSGLDSVLQKTVPWGVAFHHAGLTFEERDIIEGAFRQ
GLIRVLAATSTLSSGVNLPARRVIIRTPIFGGRPLDILTYKQMVGRAGRK
GVDTVGESILICKNSEKSKGIALLQGSLKPVRSCLQRREGEEVTGSMIRA
ILEIIVGGVASTSQDMHTYAACTFLAASMKVQLGAIEACVMWLLENEFIQ
STEAGKVYHPTHLGSATLSSSLSPADTLDIFADLQRAMKGFVLENDLHIL
YLVTPMFEDWTTIDWYRFFCLWEKLPTSMKRVAELVGVEEGFLARCVKGK
VVARTERQHRQMAIHKRFFTSLVLLDLISEVPLREINQKYGCNRGQIQSL
QQSAAVYAGMITVFSNRLGWHNMELLLSQFQKRLTFGIQRELCDLVRVSL
LNAQRARVLYASGFHTVADLARANIVEVEVILKNAVPFKSARKAVDEEEE
AVEERRNMRTIWKGLTEREAAALIVEEARMILQQDLV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9bh9 Human polymerase theta helicase positions DNA microhomologies for double-strand break repair
Resolution3.5 Å
Binding residue
(original residue number in PDB)		R179 H180
Binding residue
(residue number reindexed from 1)		R112 H113
Enzymatic activity
Enzyme Commision number 2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.6.4.12: DNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005524 ATP binding
Biological Process
GO:0006261 DNA-templated DNA replication

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Molecular Function
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Biological Process
External links
PDB RCSB:9bh9, PDBe:9bh9, PDBj:9bh9
PDBsum9bh9
PubMed
UniProtO75417|DPOLQ_HUMAN DNA polymerase theta (Gene Name=POLQ)

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