Structure of PDB 9bdv Chain A Binding Site BS02

Receptor Information

>9bdv Chain A (length=276) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

PYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTG
PGTVRISLVTKDPPHRPHPHELVGKDCRDGYYEADLCPDRSIHSFQNLGI
QCVKKRDLEQAISQRIQTNNNPFHVPIEEQRGDYDLNAVRLCFQVTVRDP
AGRPLLLTPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDK
VQKEDIEVYFTGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRV
SMQLRRPSDRELSEPMEFQYLPDTDD

Ligand information

>9bdv Chain D (length=18) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

tcactggaaattcccagt

Receptor-Ligand Complex Structure

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Structure summary

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PDB	9bdv Transient interactions modulate affinity of NF-kappaB transcription factors for DNA
Resolution	1.9 Å
Binding residue (original residue number in PDB)	Y36 C38 E39 K122 K123 R187 K221 R246 Q247
Binding residue (residue number reindexed from 1)	Y18 C20 E21 K104 K105 R169 K203 R228 Q229

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0003700	DNA-binding transcription factor activity

	Biological Process
GO:0006355	regulation of DNA-templated transcription

	Cellular Component
GO:0005737	cytoplasm

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Cellular Component

External links

PDB	RCSB:9bdv, PDBe:9bdv, PDBj:9bdv
PDBsum	9bdv
PubMed	38805268
UniProt	Q04207\|TF65_MOUSE Transcription factor p65 (Gene Name=Rela)

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