Structure of PDB 9aso Chain A Binding Site BS02

Receptor Information
>9aso Chain A (length=916) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VWIRCTHSENYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAK
AARPPWEPVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSAKA
RRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVI
EYDDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCV
KGLELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDG
GKEVLSMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIV
TNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPAQLSYAGDPQYQK
LWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTVEL
SSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCL
LQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGI
NTLINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLE
EGGLATYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMAN
CFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPN
TDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLGH
NQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAE
ELGMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMN
VCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGP
SHARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKR
FIERKYRQELKEMRWE
Ligand information
>9aso Chain C (length=24) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
KPNLHILSKLQEEMKRLAEEREET
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9aso RNAi_protein_a2
Resolution2.9 Å
Binding residue
(original residue number in PDB)		G1115 E1193 D1233 E1235 T1239 F1240 V1243
Binding residue
(residue number reindexed from 1)		G673 E751 D791 E793 T797 F798 V801
External links
PDB RCSB:9aso, PDBe:9aso, PDBj:9aso
PDBsum9aso
PubMed
UniProtQ9NRR4|RNC_HUMAN Ribonuclease 3 (Gene Name=DROSHA)

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