Structure of PDB 9asn Chain A Binding Site BS02

Receptor Information
>9asn Chain A (length=915) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VWIRCTHSENYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAK
AARPPWEPVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSAKA
RRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVI
EYDDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCV
KGLELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDG
GKEVLSMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIV
TNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPAQLSYAGDPQYQK
LWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTVEL
SSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCL
LQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGI
NTLINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLE
EGGLATYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMAN
CFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPN
TDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLGH
NQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAE
ELGMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMN
VCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGP
SHARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKR
FIERKYRQELKEMRW
Ligand information
>9asn Chain E (length=97) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auucugcucaugccagggugagguaguaaguuguauuguuguggggugcc
ccaauauaacuauacaacuuacuacuuucccugguguguggcauauu
<<....<.<<<<<<<<<<.<<<<<<<<<<<<<<<<.......<<<<..>>
>>..........>>>>>>>>>>>>>>>>>>>>>>>>>>.>....>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9asn RNAi_protein_98
Resolution3.2 Å
Binding residue
(original residue number in PDB)		I777 A785 W794 V798 R801 H802 E837 R914 Y927 G928 R938 K939 I942 E993 N1184 K1207 D1260 K1262 Q1266 R1273 S1293 H1294
Binding residue
(residue number reindexed from 1)		I335 A343 W352 V356 R359 H360 E395 R472 Y485 G486 R496 K497 I500 E551 N742 K765 D818 K820 Q824 R831 S851 H852
External links
PDB RCSB:9asn, PDBe:9asn, PDBj:9asn
PDBsum9asn
PubMed
UniProtQ9NRR4|RNC_HUMAN Ribonuclease 3 (Gene Name=DROSHA)

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