Structure of PDB 9asm Chain A Binding Site BS02

Receptor Information
>9asm Chain A (length=916) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VWIRCTHSENYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAK
AARPPWEPDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSAKARR
TGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEY
DDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKG
LELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGK
EVLSMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIVTN
PGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPAQLSYAGDPQYQKLW
KSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTVELSS
QGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQ
LAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINT
LINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEG
GLATYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCF
EALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPNTD
RQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLGHNQ
RMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEEL
GMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVC
FFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSH
ARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFI
ERKYRQELKEMRWERE
Ligand information
>9asm Chain E (length=95) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaacauugcucuaucagagugagguaguagauuguauaguugugggguac
ccuguaacuauacaaucuauugccuucccugaggaguagacuugc
.....<<<<<<<.<<<<.<.<<<<<<<<<<<<<<<<<<<.....<<<..>
>>.....>>>>>>>>>>>>>>>>>>>>.>>>>>>>>>>>......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9asm RNAi_protein_f1
Resolution2.8 Å
Binding residue
(original residue number in PDB)		W794 R801 R836 E837 R914 Y927 G928 R930 H934 M937 R938 K939 K940 G941 E993 D1029 N1184 R1213 D1260 K1262 Q1266 L1270 R1273 H1294 P1315 R1346
Binding residue
(residue number reindexed from 1)		W350 R357 R392 E393 R470 Y483 G484 R486 H490 M493 R494 K495 K496 G497 E549 D585 N740 R769 D816 K818 Q822 L826 R829 H850 P871 R902
External links
PDB RCSB:9asm, PDBe:9asm, PDBj:9asm
PDBsum9asm
PubMed
UniProtQ9NRR4|RNC_HUMAN Ribonuclease 3 (Gene Name=DROSHA)

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