Structure of PDB 8z8x Chain A Binding Site BS02

Receptor Information
>8z8x Chain A (length=620) Species: 126796 (Thogoto virus (isolate SiAr 126)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DRPDHIDSRVWELSETQEDWITQVHGHVRRVVECWKYTICCLISNMHTHR
GAPQYDVFKWQDRSTIEWICSKKKVQYPERDTPDLYDNERAVAYKVLLVS
DLSDHSPTSGIYHDLAFNLEGEAEESCALVLRGSQLQDIKGFLCRALEWV
VSNNLTQEVVETISGEAKLQFSVGTTFRTLLKRDTDWDVIPTPRVEPNVP
RIEGRRWTQMKKLPLLKEKEGPPSPWRALLLGADSEYIVCPPGTDQEAIS
WIHSQSEIECIRESKSTPASVITCLTSSLQSFAEGNPVRSRIHEDIIAFG
INKKQEKKQSASSSASGEWKRAEYQVEEMSLPPWVEEEMVLLRSDQEDNW
IELEKNAIYTEVDGVAEGLVDKYIEIVGRTKVASVIEKWQIAATRTFSQL
HTDRSRITACPIITRDPSGNCQFWGMVLLGPHHVKRDTDNAPLLIAEIMG
EDTEEKYPKHSVFSLKVEEKQFLLSLKITSFSRNKLYTFSNIRRVLIQPA
SIYSQVVLSRAAENNSLNLEVNPEIQLYLEGAQRGMTLYQWVRMILCLEF
LMAIYNNPQMEGFLANMRRLHMSRHAMMERRQVFLPFGSRPEDKVNECII
NNPIVAYLAKGWNSMPNVYY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8z8x Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses
Resolution3.06 Å
Binding residue
(original residue number in PDB)		T404 D405 H435 V436 K437 R438 D439
Binding residue
(residue number reindexed from 1)		T402 D403 H433 V434 K435 R436 D437
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0042025 host cell nucleus
GO:0044423 virion component

View graph for
Cellular Component
External links
PDB RCSB:8z8x, PDBe:8z8x, PDBj:8z8x
PDBsum8z8x
PubMed38816392
UniProtP27194|PA_THOGV Polymerase acidic protein (Gene Name=Segment)

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