Structure of PDB 8yha Chain A Binding Site BS02

Receptor Information
>8yha Chain A (length=349) Species: 1852835 (Candidatus Cloacimonetes bacterium ADurb.Bin088) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
APPNTLFLRLEGALQSWGSNEAKFALRRTADAPTKSGVLGLLCAAMGIGR
AEAADSWLPKLANLRMGVRIDRPGIRWWDFHTVGAGQRMRMKTRAETLLS
RREYLADASFLVALQGEPELVAKLSAALAKPVWAIYLGRKSCPPSRPVCE
HPPGFYNTLEEALSAVPLQKRWHNEPLPQILPCVMDWIPGYDGEHAPDDA
EIHYDLPVSFQPPRHLPRFVIRRELVVGEDVQVSRETGTSVWRPKGTRAD
YNNSEYKKVRAERLVMDHAACMVCKAPATTVQHVNYRRAGGKEIPEDLRA
LCRLCHDACTMLEYGSGMTTNRIDPCDPIWRERILAKRKEIVEFRSRGQ
Ligand information
>8yha Chain T (length=47) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tacgccaagctttttaacagtggccttattaaatgacttctcctcct
Receptor-Ligand Complex Structure
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PDB8yha Mechanisms for HNH-mediated target DNA cleavage in type I CRISPR-Cas systems
Resolution3.4 Å
Binding residue
(original residue number in PDB)
E123 T124 L126 G273 T274 R275 A276 Y278 R287 T306 T307 Q309 H310 Y313 T337 T346 T347 R349
Binding residue
(residue number reindexed from 1)
E96 T97 L99 G246 T247 R248 A249 Y251 R260 T279 T280 Q282 H283 Y286 T310 T319 T320 R322
Gene Ontology
Biological Process
GO:0051607 defense response to virus

View graph for
Biological Process
External links
PDB RCSB:8yha, PDBe:8yha, PDBj:8yha
PDBsum8yha
PubMed39047725
UniProtA0A1V6F8C5

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