Structure of PDB 8yfq Chain A Binding Site BS02

Receptor Information

>8yfq Chain A (length=1398) Species: 460519 (Komagataella phaffii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SQFPYSSAPLRSVKEVQFGLLSPEEIRAISVVKIEYPEIMDESRQRPREG
GLNDPKLGSIDRNFKCQTCGEGMAECPGHFGHMELAKPVFHIGFIPKIKK
VCECICMNCGKLLLDETNPTMAQAIRIRDPKKRFNAVWQLCKTKMVCEAD
SRGGCGNTQPVVRKDGMKLWGTWKKQPERKLLTPGEILNVFKHISPEDCF
RLGFNEDYARPEWMIITVLPVPPPQVRPSIAMDETTQGQDDLTHKLSDIL
KANINVQKLEMDGSPQHIINEVEQLLQFHVATYMDNDIAGQPQALQKSGR
PVKAIRARLKGKEGRLRGNLMGKRVDFSARTVISGDPNLELDQVGVPISI
AKTLSYPETVTQYNIHRLTEYVRNGPNEHPGAKYVIRDNGDRIDLRYHKR
AGDIVLQYGWKVERHLMDDDPVLFNRQPSLHKMSMMAHRVKVMPYSTFRL
NLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPV
MGIVQDTLCGVRKMTLRDTFIEYEQVMNMLFWVPSWDGVVPQPAILKPKP
LWTGKQLLSIAIPSGIHLQRTDGGNSLLSPKDNGMLIVDGKVMFGVVDKK
TVGSGGGGLIHTVMREKGPKICAELFGNIQKVVNYWLLHNGFSIGIGDAI
ADASTMKEITHAISSAKEQVQEIIYKAQHNELELKPGMTLRESFEGEVSR
TLNDARDSAGRSAEMNLKDLNNVKQMVSAGSKGSFINIAQMSACVGQQMV
EGKRIAFGFADRSLPHFTKDDFSPESKGFVENSYLRGLTPQEFFFHAMAG
REGLIDTAVKTAETGYIQRRLVKALEDIMVHYDGTTRNSLGDIIQFLYGE
DGLDGTQVERQTIDTIPGSDKAFHKRYYVDLMDEKNSIKPDVIEYAADIL
GDVELQKELNSEYEQLVSDRKFLREIVFVNGDHNWPLPVNLRRIIQNAQQ
IFHLDRAKASDLTIPEIIHGVRDLCKKLFVLRGENELIKEAQQNATSLFQ
CLVRARLATRRILEEFRLNRDAFEWVLGTIEAQFQRSLVHPGEMVGVIAA
QSIGEPATQMNVTLGVPRLKEILNVAKNIKTPALTVYLDREIALDIEKAK
VIQSSIEYTTLKNVTSATEIYYDPDPTSTVIEEDFDTVEAYFSPWLLRLE
LDRARMLDKQLTMNQVADKISEVFSDDLFVMWSEDNADKLIIRCRVIRDE
EDQMLKRIEAHMLDLIALRGIPGISKVYMVKHKVSVPDESGEYKNEELWA
LETDGINLAEVMAVPGVDSSRTYSNSFVEILSVLGIEATRSSLYKEILNV
IAFDGSYVNYRHMALLVDVMTSRGYLMAITRHGINRADTGALMRCSFEET
VEILFEAGAAAELDDCRGVSENVMLGQLAPMGTGAFDVMIDEKLLTSL

Ligand information

>8yfq Chain T (length=38) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

attaaaagataaagtagttgagcctggtcattactagt

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8yfq Structural basis of eukaryotic transcription termination by the Rat1 exonuclease complex.
Resolution	3.3 Å
Binding residue (original residue number in PDB)	K318 K333 R345 Q448 A833 Y837 R1389 E1406 E1407
Binding residue (residue number reindexed from 1)	K297 K312 R324 Q427 A812 Y816 R1331 E1348 E1349

External links

PDB	RCSB:8yfq, PDBe:8yfq, PDBj:8yfq
PDBsum	8yfq
PubMed	39245712
UniProt	C4R4Y0

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