Structure of PDB 8y6k Chain A Binding Site BS02

Receptor Information

>8y6k Chain A (length=741) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

NPAHAHFESFLQAQLCQDVLSSFQELCGALGLEPGGGLPQYHKIKDQLNY
WSAKSLWTKLDKRAGQPVYQQGRACTSTKCLVVGAGPCGLRVAVELALLG
ARVVLVEKRTKFSRHNVLHLWPFTIHDLRALGAKKFYGRFCTGTLDHISI
RQLQLLLLKVALLLGVEIHWGVTFTGLQPPPRKGSGWRAQLQPNPPAQLA
NYEFDVLISAAGGKFVPEGFKVREMRGKLAIGITANFVNGRTVEETQVPE
ISGVARIYNQSFFQSLLKATGIDLENIVYYKDDTHYFVMTAKKQCLLRLG
VLRQDWPDTNRLLGSANVVPEALQRFTRAAADFATHGKLGKLEFAQDAHG
QPDVSAFDFTSMMRAESSARVQEKHGARLLLGLVGDCLVEPFWPLGTGVA
RGFLAAFDAAWMVKRWAEGAESLEVLAERESLYQLLSQTSPENMHRNVAQ
YGLDPATRYPNLNLRAVTPNQVRDLYDVLGTQEELLRWCQEQTAGYPGVH
VSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATAWALKVAENE
LGITPVVSAQAVVAGSDPLGLIAYLSHFHSAFKSMAHGDLCALCGEHLYV
LERLCVNGHFFHRSCFRCHTCEATLWPGGYEQHPGDGHFYCLQHLPLRRA
KEEEMKRFCKAQTIQRRLNEIEAALRELEAEGVKLELALRRQSSSPEQQK
KLWVGQLLQLVDKKNSLVAEEAELMITVQELNLEEKQWQLD

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

8y6k Chain A Residue 2002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8y6k Autoinhibition and relief mechanisms for MICAL monooxygenases in F-actin disassembly.
Resolution	3.94 Å
Binding residue (original residue number in PDB)	C724 H750
Binding residue (residue number reindexed from 1)	C618 H644
Annotation score	1

External links

PDB	RCSB:8y6k, PDBe:8y6k, PDBj:8y6k
PDBsum	8y6k
PubMed	39122694
UniProt	Q8TDZ2\|MICA1_HUMAN [F-actin]-monooxygenase MICAL1 (Gene Name=MICAL1)

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