Structure of PDB 8xa9 Chain A Binding Site BS02
Receptor Information
>8xa9 Chain A (length=214) Species:
9606
(Homo sapiens) [
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RVPQNWFPIFNPVPLKIPLQRNVIPSVTRVLQQTMTKQQVFLLERWKQRM
ILELGEDGFKEYTSNVFLQGKRFHEALESILSSGYIESVQHILKDVSGVR
ALESAVQHETLNYIGLLDCVAEYQGKLCVIDWKTSEKPKPFIQSTFDNPL
QVVAYMGAMNHDTNYSFQVQCGLIVVAYKDGSPAHPHFMDAELCSQYWTK
WLLRLEEYTEKKKN
Ligand information
>8xa9 Chain E (length=10) [
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tttttttgct
Receptor-Ligand Complex Structure
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PDB
8xa9
Structural basis of how MGME1 processes DNA 5' ends to maintain mitochondrial genome integrity.
Resolution
2.32 Å
Binding residue
(original residue number in PDB)
S132 T134 Q138 Q145 F147 L148 L149 W152 V172 F173 G176 H180 G235 K253 T254 F266 Y275
Binding residue
(residue number reindexed from 1)
S26 T28 Q32 Q39 F41 L42 L43 W46 V66 F67 G70 H74 G115 K133 T134 F146 Y155
Enzymatic activity
Enzyme Commision number
3.1.-.-
External links
PDB
RCSB:8xa9
,
PDBe:8xa9
,
PDBj:8xa9
PDBsum
8xa9
PubMed
38471810
UniProt
Q9BQP7
|MGME1_HUMAN Mitochondrial genome maintenance exonuclease 1 (Gene Name=MGME1)
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