Structure of PDB 8wxz Chain A Binding Site BS02

Receptor Information
>8wxz Chain A (length=1079) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEWIHEKSPKHNSYDIIEKRYNEEFKMTYTVYQHKKAKTQVISLGTNDPL
DVEQAFAFYVKTLTHSGKGIPHILQHSVLSGSKNYNYKNSIGLLEKGTLH
THLNAYTFNDRTVYMAGSMNNKDFFNIMGVYMDSVFQPNVLENKYIFETE
GWTYEVEKLKEDEKGKAEIPQMKDYKVSFNGIVYNEMKGALSSPLEDLYH
EEMKYMFPDNVHSNNSGGDPKEITNLTYEEFKEFYYKNYNPKKVKVFFFS
KNNPTELLNFVDQYLGQLDYSKYRDDAVESVEYQTYKKGPFYIKKKYGDH
SEEKENLVSVAWLLNPKVSLENPTDYFVLLIINNLLIHTPESVLYKALTD
CGLGNNVIDRGLNDSLVQYIFSIGLKGIKRNNEKIKNFDKVHYEVEDVIM
NALKKVVKEGFNKSAVEASINNIEFILKEANLKTSKSIDFVFEMTSKLNY
NRDPLLIFEFEKYLNIVKNKIKNEPMYLEKFVEKHFINNAHRSVILLEGD
ENYAQEQENLEKQELKKRIENFNEQEKEQVIKNFEELSKYKNAEESPEHL
NKFPIISISDLNKKTLEVPVNVYFTNINENNNIMETYNKLKTNEHMLKDN
MDVFLKKYVLKDYSFTETKYEGNVPILVYEMPTTGIVYLQFVFSLDHLTV
DELAYLNLFKTLILENKTNKRSSEDFVILREKNIGSMSANVALYSKDDHL
NVTDKYNAQALFNLEMHVLSHKCNDALNIALEAVKESDFSNKKKVIDILK
RKINGMKTTFSEKGYAILMKYVKAHLNSKHYAHNIIYGYENYLKLQEQLE
LAENDFKTLENILVRIRNKIFNKKNLMVSVTSDYGALKHLFVNSNESLKN
LVSYFEENDKYINMGWNEEIKSKKLFDEEKVKKEFFVLPTFVNSVSMSGI
LFKPGEYLDPSFTVIVAALKNSYLWDTVRGLNGAYGVFADIEYDGSVVFL
SARDPNLEKTLATFRESAKGLRKMADTMTENDLLRYIINTIGTIDKPRRG
IELSKLSFLRLISNESEQDRVEFRKRIMNTKKEDFYKFADLLESKVNEFE
KNIVIITTKEKANEYIANVDGEFKKVLIE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8wxz Chain A Residue 1203 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8wxz Falcilysin in complex with hemoglobin alpha chain peptide
Resolution2.3 Å
Binding residue
(original residue number in PDB)		H129 H133 E243
Binding residue
(residue number reindexed from 1)		H72 H76 E186
Annotation score4
External links
PDB RCSB:8wxz, PDBe:8wxz, PDBj:8wxz
PDBsum8wxz
PubMed
UniProtQ76NL8|FCLN_PLAF7 Falcilysin (Gene Name=FLN)

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