Structure of PDB 8wmi Chain A Binding Site BS02

Receptor Information
>8wmi Chain A (length=1237) Species: 45657 (Desulfonema ishimotonii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MTTTMKISIEFLEPFRMTKWQESTRRNKNNKEFVRGQAFARWHRNKKDNT
KGRPYITGTLLRSAVIRSAENLLTLSDGKISEKTCCPGKFDTEDKDRLLQ
LRQRSTLRWTDKNPCPDNAETYCPFCELLGRSFRIHFGNLSLPGKPDFDG
PKAIGSQRVLNRVDFKSGKAHDFFKAYEVDHTRFPRFEGEITIDNKVSAE
ARKLLCDSLKFTDRLCGALCVIRFDNLAEKTAEQIISILDDNKKTEYTRL
LADAIRSLRRSSKLVAGLPKDHDGKDDHYLWDIGTIRQILTTSADTKELK
NAGKWREFCEKLGEALYLKSKSVLKETVVCGELVAKTPFFFGAIDEDAKQ
TALQVLLTPDNKYRLPRSAVRGILRRDLQTYFDSPCNAELGGRPCMCKTC
RIMRGITVMDARSEYNAPPEIRHRTRINPFTGTVAEGALFNMEVAPEGIV
FPFQLRYRGSEDGLPDALKTVLKWWAEGQAFMSGAASTGKGRFRMENAKY
ETLDLSDENQRNDYLKNWGWRDEKGLEELKKRLNSGLPEPGNYRDPKWHE
INVSIEMASPFINGDPIRAAVDKRGTAVVTFVKYKAEGEEAKPVCAYKAE
SFRGVIRSAVARIHMEDGVPLTELTHSDCECLLCQIFGSEYEAGKIRFED
LVFESDPEPVTFDHVAIDRFTGGAADKKKFDDSPLPGSPARPLMLKGSFW
IRRDVLEDEEYCKALGKALADVNNGLYPLGGKSAIGYGQVKSLGIKGDDK
RISRLMNAVPEKPKTDAEVRIEAEKVYYPHYFVEPHKKVEREEKPCGHQK
FHEGRLTGKIRCKLITKTPLIVPDTSNDDFFRPYHKSYAFFRLHKQIMIP
GSELRGMVSSVYETVTNSCFRIFDETKRLSWRMDADQDFLPGRVTADGKH
IQKFSETEEYEIPEKARIKYKELLRVYNNNPQADLVYFKHNEKYVEDIVP
VRISRTVDDRMIGKRMSADLRPCHGGLCPACRLFGTGSYKGRVRFGFASL
ENDPEWLIPGKNPGDPFHGGPVMLSLLERPRPTWSIPGSDNKFKVPGRKF
YVHHHAWKTIKDGNHPTTGKAIEQSPNNRTVEALAGGNSFSFEIAFENLK
EWELGLLIHSLQLEKGLAHKLGMAKSMGFGSVEIDVESVRLRKDWKQWRN
GNSEIPNWLGKGFAKLKEWFRDELDFIENLKKLLWFPEGDQAPRVCYPML
RKKDDPNGNSGYEELKDGEFKKEDRQKKLTTPWTPWA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8wmi Chain A Residue 1701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8wmi Structural basis of negative regulation of CRISPR-Cas7-11 by TPR-CHAT.
Resolution3.53 Å
Binding residue
(original residue number in PDB)		C86 C126
Binding residue
(residue number reindexed from 1)		C86 C126
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

View graph for
Biological Process
External links
PDB RCSB:8wmi, PDBe:8wmi, PDBj:8wmi
PDBsum8wmi
PubMed38735995
UniProtA0A401FT36

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