Structure of PDB 8wg0 Chain A Binding Site BS02

Receptor Information
>8wg0 Chain A (length=682) Species: 376686 (Flavobacterium johnsoniae UW101) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDLKSPDGNFLMHFSLEADGTPVYKLIYKGKDVIKASKLGFTLKNDNKSL
LNDFKIEDTKTSSFDENWKPVWGEVSSIRNNYNELAVSLSQKETDRKMII
RFRLFDDGLGFRYEFPQQNNLIYFTIKEERTQFAMAGDHTAYWIPGDYDT
QEYNYSTSKLSEIRGLMEKAYTKGNASQTSFSPTGVQTSLMMKSQDGLYI
NLHEAALINYSCMHLNLDDKNFVFESWLTPDSHGDKGKMQAPCKTPWRTV
IVSDDARNILASKLTYNLNEPSKIQETSWIKPTKYVGVWWEMISGKSTWS
YTDEFPSVQLGVTDFSKAKPNRKHGATTANVKRYIDFAAKNGFDAVLVEG
WNEGWEDWIGHEKDYVFDFVTPYPDFDIKGLNEYAHAKKVKLIMHHETSG
AVRNYERHMDAAYKLMKQYGYDAVKSGYVGNILPLGETHYSQWTNNHYQY
AIEKAADYQIMVNAHEAVRPTGIARTYPNLIGNEAARGTEYQAFGNDRNN
ANHVTILPFTRLIGGPMDYTPGIFEMDVTNGSHVNATIANQLALYVTMYS
PLQMAADFPENYERFADAFQFIKDVAVDWDDSRYLEAEPGQYITVARKAK
GTDNWFLGNVNGETARVSNIDLGFLEKGKKYTAVIYADAKDANYKTNTQA
YTIRKVVVTSNSKLSQFSASGGGYAISFYPVA
Ligand information
Ligand IDGLC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-DVKNGEFBSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-glucopyranose;
alpha-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL423707
DrugBank
ZINCZINC000003861213
PDB chain8wg0 Chain A Residue 802 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8wg0 Structural insights into alpha-(1->6)-linkage preference of GH97 glucodextranase from Flavobacterium johnsoniae.
Resolution1.95 Å
Binding residue
(original residue number in PDB)		W308 E368 W374 W377 H414 E416 K444 V448 H484 E485 E503 E509
Binding residue
(residue number reindexed from 1)		W289 E349 W355 W358 H395 E397 K425 V429 H465 E466 E484 E490
Annotation score4
Enzymatic activity
Enzyme Commision number 3.2.1.70: glucan 1,6-alpha-glucosidase.
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0030246 carbohydrate binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8wg0, PDBe:8wg0, PDBj:8wg0
PDBsum8wg0
PubMed38661728
UniProtA5FBI0

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