Structure of PDB 8wfp Chain A Binding Site BS02

Receptor Information
>8wfp Chain A (length=225) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AAHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDK
YGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPN
SLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSA
IILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEY
GCCKELASRLRYARTMVDKLLSSRS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8wfp Degradation of Polo-like Kinase 1 by the Novel Poly-Arginine N-Degron Pathway PROTAC Regulates Tumor Growth in Nonsmall Cell Lung Cancer.
Resolution1.99 Å
Binding residue
(original residue number in PDB)		L490 L491
Binding residue
(residue number reindexed from 1)		L120 L121
External links
PDB RCSB:8wfp, PDBe:8wfp, PDBj:8wfp
PDBsum8wfp
PubMed38105611
UniProtP53350|PLK1_HUMAN Serine/threonine-protein kinase PLK1 (Gene Name=PLK1)

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