Structure of PDB 8vq2 Chain A Binding Site BS02

Receptor Information
>8vq2 Chain A (length=1037) Species: 10298 (Human alphaherpesvirus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TGPTQRHTYYSECDEFRFIAPRVLDEDAPPEKRAGVHDGHLKRAPKVYCG
GDERDVLRVGSGGFWPRRSRLWGGVDHAPAGFNPTVTVFHVYDILENVEH
AYGMRAAQFHARFMDAITPTGTVITLLGLTPEGHRVAVHVYGTRQYFYMN
KEEVDRHLQCRAPRDLCERMAAALRESPGASFRGISADHFEAEVVERTDV
YYYETRPALFYRVYVRSGRVLSYLCDNFCPAIKKYEGGVDATTRFILDNP
GFVTFGWYRLKPGRNNTLAQPRAPMAFGTSSDVEFNCTADNLAIEGGMSD
LPAYKLMCFDIACKAGGEDELAFPVAGHPEDLVIQISCLLYDLSTTALEH
VLLFSLGSCDLPESHLNELAARGLPTPVVLEFDSEFEMLLAFMTLVKQYG
PEFVTGYNIINFDWPFLLAKLTDIYKVPLDGYGRMNGRGVFRVWDKRSKI
KVNGMVNIDMYGIITDKIKLSSYKLNAVAEAVLKDKKKDLSYRDIPAYYA
AGPAQRGVIGEYCIQDSLLVGQLFFKFLPHLELSAVARLAGINITRTIYD
GQQIRVFTCLLRLADQKGFILPDTQVGYQGARVHDPTSGFHVNPVVGFDF
ASLYPSIIQAHNLCFSTLSLRADAVAHLEAGKDYLEIEVGGRRLFFVKAH
VRESLLSILLRDWLAMRKQIRSRIPQSSPEEAVLLDKQQAAIKVVCNSVY
GFTGVQHGLLPCLHVAATVTTIGREMLLATREYVHARWAAFEQLLADFPE
AADMRAPGPYSMRIIYGDTDSIFVLCRGLTAAGLTAMGDKMASHISRALF
LPPIKLECEKTFTKLLLIAKKKYIGVIYGGKMLIKGVDLVRKNNCAFINR
TSRALVDLLFYDDTVSGAAAALAERPAEEWLARPLPEGLQAFGAVLVDAH
RRITDPERDIQDFVLTAELSRHPRAYTNKRLAHLTVYYKLMARRAQVPSI
KDRIPYVIVAQTREVEETVARLAALRELVSELAEDPAYAIAHGVALNTDY
YFSHLLGAACVTFKALFGNNAKITESLLKRFIPEVWH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8vq2 Discovery of Broad-Spectrum Herpes Antiviral Oxazolidinone Amide Derivatives and Their Structure-Activity Relationships.
Resolution3.829 Å
Binding residue
(original residue number in PDB)
K534 D886 D888 Y941 K953 V958 R959 E1036 R1039 Y1044 T1045 R1071
Binding residue
(residue number reindexed from 1)
K469 D768 D770 Y823 K835 V840 R841 E918 R921 Y926 T927 R953
External links