Structure of PDB 8v1r Chain A Binding Site BS02

Receptor Information
>8v1r Chain A (length=1087) Species: 10306 (Human alphaherpesvirus 1 strain KOS) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPTQRHTYYSECDEFRFIAPRVLDEDAPPEKRAGVHDGHLKRAPKVYCGG
DERDVLRVGSGGFWPRRSRLWGGVDHAPAGFNPTVTVFHVYDILENVEHA
YGMRAAQFHARFMDAITPTGTVITLLGLTPEGHRVAVHVYGTRQYFYMNK
EEVDRHLQCRAPRDLCERMAAALRESPGASFRGISADHFEAEVVERTDVY
YYETRPALFYRVYVRSGRVLSYLCDNFCPAIKKYEGGVDATTRFILDNPG
FVTFGWYRLKPGRNNTLAQPRAPMAFGTSSDVEFNCTADNLAIEGGMSDL
PAYKLMCFDIECKAGGEDELAFPVAGHPEDLVIQISCLLYDLSTTALEHV
LLFSLGSCDLPESHLNELAARGLPTPVVLEFDSEFEMLLAFMTLVKQYGP
EFVTGYNIINFDWPFLLAKLTDIYKVPLDGYGRMNGRGVFRVWDIGQSHF
QKRSKIKVNGMVNIDMYGIITDKIKLSSYKLNAVAEAVLKDKKKDLSYRD
IPAYYATGPAQRGVIGEYCIQDSLLVGQLFFKFLPHLELSAVARLAGINI
TRTIYDGQQIRVFTCLLRLADQKGFILPDTQGRFRGRHVGYQGARVLDPT
SGFHVNPVVVFDFASLYPSIIQAHNLCFSTLSLRADAVAHLEAGKDYLEI
EVGGRRLFFVKAHVRESLLSILLRDWLAMRKQIRSRIPQSSPEEAVLLDK
QQAAIKVVCNSVYGFTGVQHGLLPCLHVAATVTTIGREMLLATREYVHAR
WAAFEQLLADFPEAADMRAPGPYSMRIIYGDTDSIFVLCRGLTAAGLTAM
GDKMASHISRALFLPPIKLECEKTFTKLLLIAKKKYIGVIYGGKMLIKGV
DLVRKNNCAFINRTSRALVDLLFYDDTVSGAAAALAERPAEEWLARPLPE
GLQAFGAVLVDAHRRITDPERDIQDFVLTAELSRHPRAYTNKRLAHLTVY
YKLMARRAQVPSIKDRIPYVIVAQTREVEETVARLARKLLVSELAEDPAY
AIAHGVALNTDYYFSHLLGAACVTFKALFGNNAKITESLLKRFIPEVWHP
PDDVAARLRAAGFGAVGAGATAEETRRMLHRAFDTLA
Ligand information
Receptor-Ligand Complex Structure
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PDB8v1r Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance.
Resolution2.9 Å
Binding residue
(original residue number in PDB)
W502 F509 Q510 K511 K514 G616 Q617 Q618 Q640 R644 R692 V694 G695 Y696 G698 V701 N815 S816 G819 G822 V823 K938 K940 R1048 L1138 V1139 S1140 H1164 V1171 K1174
Binding residue
(residue number reindexed from 1)
W443 F450 Q451 K452 K455 G557 Q558 Q559 Q581 R585 R587 V589 G590 Y591 G593 V596 N710 S711 G714 G717 V718 K833 K835 R943 L990 V991 S992 H1016 V1023 K1026
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