Structure of PDB 8uel Chain A Binding Site BS02

Receptor Information

>8uel Chain A (length=433) Species: 6689 (Penaeus vannamei)

SITKVFARTIFDSRGNPTVEVDLYTHKGLFRAAVPSGASTGVHEALEMRD
GDKSKYHGKSVFKAVNNVNSIIAPEIIKSGLKVTQQKECDDFMRKLDGTE
NKSRLGANAILGVSLAICKAGAAELGIPLYRHIANLANYSDVILPVPAFN
VINGGSHAGNKLAMQEFMILPTGASSFTEAMRMGSEVYHHLKAVIKGRFG
LDATAVGDEGGFAPNILNNKDALTLIQESIEKAGYTGKIEIGMDVAASEF
YKGENIYDLDFKTANNDGSQKITGDQLRDMYMEFCNEFPIVSIEDPFDQD
DWENWTKMTSATNIQIVGDDLTVTNPKRIATAVEKKACNCLLLKVNQIGS
VTESIDAHLLAKKNGWGTMVSHRSGETEDCFIADLVVGLCTGQIKTGAPC
RSERLAKYNQILRIEEELGSNAKFAGKKFRKPC

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 8uel Chain A Residue 502

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8uel Characterization and Structural Analyses of Enolase from Shrimp ( Litopenaeus vannamei ).
• Resolution: 2.49 Å
• Binding residue (original residue number in PDB): D244 E294 D319
• Binding residue (residue number reindexed from 1): D244 E294 D319
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 4.2.1.11: phosphopyruvate hydratase.

Gene Ontology

Molecular Function

• GO:0000287 magnesium ion binding
• GO:0004634 phosphopyruvate hydratase activity
• GO:0016829 lyase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0006096 glycolytic process

Cellular Component

• GO:0000015 phosphopyruvate hydratase complex

External links

• PDB: RCSB:8uel, PDBe:8uel, PDBj:8uel
• PDBsum: 8uel
• PubMed: 38033172
• UniProt: O96656