Structure of PDB 8uau Chain A Binding Site BS02

Receptor Information
>8uau Chain A (length=332) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FYRCGYCKNESGSRSNGMWAHSMTVQDYQDLIDRGWRRSGKYVYKPVMNQ
TCCPQYTIRCRPLQFQPSKSHKKVLKKMLKFLAKGEVPKGSCEPPCRKAK
EIRKERKRLKLMQQNPAGELEGFQALFPPKAKSNQPKSLEDLIFESLPEN
ASHKLEVRLVPVSFEDPEFKSSFSQSFSLYVKYQVAIHQDPPDECGKTEF
TRFLCSSPLEAETPPNGPDCGYGSFHQQYWLDGKIIAVGVIDILPNCVSS
VYLYYDPDYSFLSLGVYSALREIAFTRQLHEKTSQLSYYYMGFYIHSCPK
MKYKGQYRPSDLLCPETYVWVPIEQCLPSLEN
Ligand information
>8uau Chain R (length=76) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggcucuguggcgcaauggauagcgcauuggacuucuaauucaaagguugu
ggguucgaaucccaccagagucgcca
<<<<<<<..<<<<........>>>>..<<...........>>......<<
<<<.......>>>>>>>>>>>>....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8uau Oligomerization and a distinct tRNA-binding loop are important regulators of human arginyl-transferase function.
Resolution5.7 Å
Binding residue
(original residue number in PDB)		K88 S89 K91 K95 E112 C205 R206 K207 A208 I211 R212 R215 Q222 Q223 P251 Y298 Y369 Y370 D371 V381 Y418 K419
Binding residue
(residue number reindexed from 1)		K69 S70 K72 K76 E93 C96 R97 K98 A99 I102 R103 R106 Q113 Q114 P136 Y183 Y254 Y255 D256 V266 Y303 K304
External links
PDB RCSB:8uau, PDBe:8uau, PDBj:8uau
PDBsum8uau
PubMed39068213
UniProtO95260|ATE1_HUMAN Arginyl-tRNA--protein transferase 1 (Gene Name=ATE1)

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