Structure of PDB 8u9x Chain A Binding Site BS02

Receptor Information

>8u9x Chain A (length=1398) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGG
LNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKV
CECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCETDV
PSRGCGNTQPTIRKDGLKLVGSWKELRVLSTEEILNIFKHISVKDFTSLG
FNEVFSRPEWMILTCLPVPPPPVRPSISFQRGEDDLTFKLADILKANISL
ETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSPVKSIRAR
LKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPE
VVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQY
GWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPY
NADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTL
CGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQIL
SVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGG
LIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMRE
ITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDK
AGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFG
FVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTA
VKTAEPGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHI
EKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVL
LDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKP
SDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLAT
RRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQ
MTLNTFHFAGVASKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQ
EQAKLIRSAIEHTTLKSVTIASEIYYDPTVIPEDEEIIQLQQSPWLLRLE
LDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVEED
HMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLE
TDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIA
SDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVE
ILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMIDEESLVKYMP

Ligand information

>8u9x Chain T (length=13) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

acgtccctctcga

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8u9x Structural basis of transcription: RNA polymerase II substrate binding and metal coordination using a free-electron laser.
Resolution	3.05 Å
Binding residue (original residue number in PDB)	F252 R344 R350 Q447 P448 T831 A832 G835 R1386 E1403
Binding residue (residue number reindexed from 1)	F229 R316 R322 Q419 P420 T803 A804 G807 R1329 E1346

External links

PDB	RCSB:8u9x, PDBe:8u9x, PDBj:8u9x
PDBsum	8u9x
PubMed	39190355
UniProt	P04050\|RPB1_YEAST DNA-directed RNA polymerase II subunit RPB1 (Gene Name=RPO21)

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