Structure of PDB 8tyg Chain A Binding Site BS02

Receptor Information
>8tyg Chain A (length=405) Species: 126793 (Plasmodium vivax Sal-1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KDLLYKYKLYGDIDEYAYYFLDIDIGTPEQRISLILDTGSSSLSFPCAGC
KNCGVHMENPFNLNNSKTSSILYCENEECPFKLNCVKGKCEYMQSYCEGS
QISGFYFSDVVSVVSYNNERVTFRKLMGCHMHEESLFLYQQATGVLGMSL
SKPQGIPTFVNLLFDNAPQLKQVFTICISENGGELIAGGYDPAYIVRALR
EAEKVVWENVTRKYYYYIKVRGLDMFGTNMMSSSKGLEMLVDSGSTFTHI
PEDLYNKLNYFFDILCIQDMNNAYDVNKRLKMTNESFNNPLVQFDDFRKS
LKSIIAKENMCVKIVDGVQCWKYLEGLPDLFVTLSNNYKMKWQPHSYLYK
KESFWCKGIEKQVNNKPILGLTFFKNRQVIFDIQKNRIGFVDANCPSHPT
HTRPR
Ligand information
Ligand IDTEW
InChIInChI=1S/O6Te.H2O.17O.6W/c1-7(2,3,4,5)6;;;;;;;;;;;;;;;;;;;;;;;;/h;1H2;;;;;;;;;;;;;;;;;;;;;;;/q;;;;;;;;;;;;;6*-1;;;;;;+1/p-1
InChIKeyJDLYBIMRCSJRQJ-UHFFFAOYSA-M
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6[O-]=[W]123(O[W]45(=O)(O1[Te]6789O2[W]1(=O)(O3)(O6[W]2(=O)(O1)(O7[W]1(=O)(O2)(O8[W](=O)(O94)(O5)(O1)[O-])[O-])[O-])[O-])[O-])[O]
FormulaO24 Te W6
Name6-tungstotellurate(VI)
ChEMBL
DrugBank
ZINC
PDB chain8tyg Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8tyg Plasmodium vivax PMV-WM08 inhibitor complex
Resolution1.64 Å
Binding residue
(original residue number in PDB)		K195 R283 K284 Y285 Y286
Binding residue
(residue number reindexed from 1)		K152 R212 K213 Y214 Y215
Annotation score1
External links
PDB RCSB:8tyg, PDBe:8tyg, PDBj:8tyg
PDBsum8tyg
PubMed
UniProtA5K302|PLM5_PLAVS Plasmepsin V (Gene Name=PMV)

[Back to BioLiP]