Structure of PDB 8ts0 Chain A Binding Site BS02

Receptor Information
>8ts0 Chain A (length=129) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GCPVNWVEHERSCYWFSRSGKAWADADNYCRLEDAHLVVVTSWEEQKFVQ
HHIGPVNTWMGLHDQNGPWKWVDGTDYETGFKNWRPEQPDDWYGHGLGGG
EDCAHFTDDGRWNDDVCQRPYRWVCETEL
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8ts0 Chain A Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ts0 Targeted protein degradation systems to enhance Wnt signaling.
Resolution1.7 Å
Binding residue
(original residue number in PDB)		Q240 D242 E253 N265 D266
Binding residue
(residue number reindexed from 1)		Q88 D90 E101 N113 D114
Annotation score4
External links
PDB RCSB:8ts0, PDBe:8ts0, PDBj:8ts0
PDBsum8ts0
PubMed38847394
UniProtP07306|ASGR1_HUMAN Asialoglycoprotein receptor 1 (Gene Name=ASGR1)

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