Structure of PDB 8ti7 Chain A Binding Site BS02
Receptor Information
>8ti7 Chain A (length=132) Species:
6956
(Dermatophagoides pteronyssinus) [
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GSGSWQSYVDNQICQHVDCTLAAIANIQDGSIWAKFEKDDKKISPKELKT
IADTIRQNPNGFLETGIHIGGEKYICIQADNQLVRGRRGSSALCIVATNT
CLLAAATVDGYPAGQLNNVIEKLGDYLRSNNY
Ligand information
>8ti7 Chain N (length=12) Species:
32630
(synthetic construct) [
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PPPPPPPPPPPP
Receptor-Ligand Complex Structure
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PDB
8ti7
Structural homology of mite profilins to plant profilins is not indicative of allergic cross-reactivity.
Resolution
2.397 Å
Binding residue
(original residue number in PDB)
N129 Y130
Binding residue
(residue number reindexed from 1)
N131 Y132
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003779
actin binding
GO:0003785
actin monomer binding
Biological Process
GO:0042989
sequestering of actin monomers
GO:0044087
regulation of cellular component biogenesis
GO:0051128
regulation of cellular component organization
Cellular Component
GO:0005856
cytoskeleton
GO:0005938
cell cortex
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Cellular Component
External links
PDB
RCSB:8ti7
,
PDBe:8ti7
,
PDBj:8ti7
PDBsum
8ti7
PubMed
38662449
UniProt
A0A2L0EBJ5
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