Structure of PDB 8tci Chain A Binding Site BS02

Receptor Information
>8tci Chain A (length=283) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KRRPIRVLSLFDGIATGYLVLKELGIKVEKYIASEVCAESIAVGTVKHEG
QIKYVDDIRNITKEHIDEWGPFDLVIGGSPCNDLSCVNPVRKGLFEGTGR
LFFEFYRLLNYSCPEEEDDRPFFWMFENVVAMEVGDKRDISRFLECNPVM
IDAIKVSAAHRARYFWGNLPGMNRPVMASKNDKLELQDCLEFSRTAKLKK
VQTITTKSNSIRQGKNQLFPVVMNGKDDVLWCTELERIFGFPEHYTDVSN
MGRGARQKLLGRSWSVPVIRHLFAPLKDHFACE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8tci The structure of DNA methyltransferase DNMT3C reveals an activity-tuning mechanism for DNA methylation.
Resolution3.19 Å
Binding residue
(original residue number in PDB)
S536 C538 N539 C543 V544 N545 E584 N585 V586 R620 Q659 T660 T663 K664 G718 R719
Binding residue
(residue number reindexed from 1)
S79 C81 N82 C86 V87 N88 E127 N128 V129 R163 Q202 T203 T206 K207 G261 R262
External links
PDB RCSB:8tci, PDBe:8tci, PDBj:8tci
PDBsum8tci
PubMed39098534
UniProtP0DOY1|DNM3C_MOUSE DNA (cytosine-5)-methyltransferase 3C (Gene Name=Dnmt3c)

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