Structure of PDB 8t4r Chain A Binding Site BS02

Receptor Information
>8t4r Chain A (length=75) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SGYWITCCPTCDVDINTWVPFYSTELNKPAMIYCSHGDGHWVHAQCMDLA
ERTLIHLSAGSNKYYCNEHVEIARA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8t4r Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8t4r Trimethyllysine Reader Proteins Exhibit Widespread Charge-Agnostic Binding via Different Mechanisms to Cationic and Neutral Ligands.
Resolution1.2 Å
Binding residue
(original residue number in PDB)		C419 C423 H455 C458
Binding residue
(residue number reindexed from 1)		C7 C11 H43 C46
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006310 DNA recombination
Cellular Component
GO:0005634 nucleus

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Cellular Component
External links
PDB RCSB:8t4r, PDBe:8t4r, PDBj:8t4r
PDBsum8t4r
PubMed38266163
UniProtP55895|RAG2_HUMAN V(D)J recombination-activating protein 2 (Gene Name=RAG2)

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