Structure of PDB 8t2j Chain A Binding Site BS02

Receptor Information
>8t2j Chain A (length=339) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAGLYSLRVSVFSDQGGRKYMEDVTQIVVEPEETAERSSVAFFAVCDGHG
GREAAQFAREHLWGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAMWKKLA
EWPKTMTGLPSTSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDKDDFVRA
VEVTQDHKPELPKERERIEGLGGSVMNKSGVNRVVWKRPALTHNGPVAAS
TVIDQIPFLAVARALGDLWSYDFFSGEFVVSPEPDTSVHTLDPQKHKYII
LGSDGLWNMIPPQDAISMCQDQEEKKYLMGEHGQSCAKMLVNRALGRWRQ
RMLRADNTSAIVICISPEVDNTNEDELYLNLTDSPSYNS
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8t2j Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8t2j Structure of the catalytic domain of PPM1D/Wip1 serine/threonine phosphatase
Resolution1.8 Å
Binding residue
(original residue number in PDB)		D105 D314 D366
Binding residue
(residue number reindexed from 1)		D47 D254 D306
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
External links
PDB RCSB:8t2j, PDBe:8t2j, PDBj:8t2j
PDBsum8t2j
PubMed39002674
UniProtO15297|PPM1D_HUMAN Protein phosphatase 1D (Gene Name=PPM1D)

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