Structure of PDB 8slp Chain A Binding Site BS02

Receptor Information
>8slp Chain A (length=910) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CKGEVNFKRSKFVKVPSNVAPSMLFELLLTEWHLPAPNLVVSLVGEERLF
AMKSWLRDVLRKGLVKAAQSTGAWILTSALHVGLARHVGQAVRDHSLAVR
VVAIGMASLDRILHRQLLDGTPIHYPADCPLDSNLSHFILVAELQLSLEK
HISQQRSSIQIPVLCLLVNGDPSTLERMSRAVEQAAPWLILGGIADVLAA
LVGQPHLLVPQVTEKQFREKFPSECFSWEAIVHWTELLQNIAAHPHLLTV
YDFEQEGSEDLDTVILKALVKACKSHSRDAQDYLDELKLAVAWDRVDIAK
SEIFNGDVEWKSCDLEEVMTDALVSNKPDFVRLFVDSGADMAEFLTYGRL
QQLYHSVSPKSLLFELLERKHEEGRLLPAFSLHEVSRVLKDFLHDACRGF
YQWLPDLSRKSEDPWRDLFLWAVLQNRYEMATYFWAMGREGVAAALAACK
IIKEMSHLEKEAEVARTMREAKYEQLALDLFSECYSNSEDRAFALLVRRN
HSWSRTTCLHLATEADAKAFFAHDGVQAFLTKIWWGDMATGTPILRLLGA
FTCPALIYTNLISFSEAAFLLTRWRKFWGAPVTVFLGNVVMYFAFLFLFS
YVLLVDFRPPPQGPSGSEVTLYFWVFTLVLEEIRQGFFTDTRLVKKFTLY
VEDNWNKCDMVAIFLFIVGVTCRMVPSVFEAGRTVLAIDFMVFTLRLIHI
FAIHKQLGPKIIIVERMMKDVFFFLFFLSVWLVAYGVTTQALLHPHDGRL
EWIFRRVLYRPYLQIFGQIPLDEIDEARVLYANWLVILLLVTFLLVTNVL
LMNLLIAMFSYTFQVVQGNADMFWKFQRYHLIVEYHGRPALAPPFILLSH
LSLVLKQVFRPDPVDQKIITWETVQKENFLSTMEKRRRDSEEEVLRKTAH
RVDLIAKYIG
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8slp Chain A Residue 1202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8slp Structural dynamics at cytosolic interprotomer interfaces control gating of a mammalian TRPM5 channel.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		N807 D810
Binding residue
(residue number reindexed from 1)		N656 D659
Annotation score4
External links